Now there is no excuse to avoid the gym: just one hour of exercise instantly changes your genes to boost the breakdown of fat. Juleen Zierath and Romain Barres at the Karolinska Institute in Stockholm, Sweden, and colleagues looked for epigenetic changes -the addition of a methyl group to genes - in muscle cells during strenuous exercise. To do so, the team collected biopsies from the thigh muscles of eight men who led relatively sedentary lives, both before and after an hour of exercise.
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