DNA webs-the replicators for all things tiny

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DNA webs-the replicators for all things tiny

机译：DNA网-微小事物的复制者

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It's dna replication - but not as we know it. Elaborate webs of ONA have been made that can copy themselves outside cells. Unlike DNA in nature, which replicates inside cells, these webs exist freely and suggest how self-replication might one day be an alternative to conventional fabrication for very tiny structures. A self-copying DNA double-helix would not be news. Living cells have been doing this for billions of years, and researchers have done it in test tubes for decades. But in a new twist, a team led by Paul Chaikin of New York University has created elaborate webs of DNA never seen in nature and persuaded these structures to make exact copies of themselves.

机译：这是dna复制-但据我们所知并非如此。制作了精心制作的ONA网站，可以将自己复制到单元外。与自然界中在细胞内复制的DNA不同，这些网自由地存在，并暗示着有一天自我复制可能会替代非常微小的结构的常规制造方法。自我复制的DNA双螺旋结构不是新闻。活细胞已经做到了数十亿年，而研究人员已经在试管中做到了数十年。但是，由纽约大学的保罗·柴金（Paul Chaikin）领导的一个小组又进行了一次新的尝试，他们创造了精心制作的，从未在自然界见过的DNA网络，并说服了这些结构来精确复制自己。

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《New scientist》 |2011年第2834期|p.10|共1页
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收录信息美国《科学引文索引》(SCI);美国《化学文摘》(CA);
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正文语种 eng
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1. The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress The kinase domain residue serine 173 of Schizosaccharomyces pombe Chk1 kinase is critical for the response to DNA replication stress [J] . Naomi Coulton, Thomas Caspari Biology Open . 2017,第12期

机译：粟酒裂殖酵母Chk1激酶的激酶结构域残基丝氨酸173对DNA复制压力的响应至关重要粟酒裂殖酵母Chk1的激酶结构域残基丝氨酸173对DNA复制应激的反应至关重要。激酶对于DNA复制压力的反应至关重要
2. DNA DamageDNA damage and DNA Replication StressDNA replication stress in Yeast Models of Aging. [J] . William C Burhans, Martin Weinberger Sub-cellular biochemistry . 2012,第Null期

机译：DNA损伤DNA损伤和DNA复制应力酵母老化模型中的DNA复制应力。
3. DNA REPLICATION MACHINERY - FUNCTIONAL CHARACTERIZATION OF A COMPLEX CONTAINING DNA POLYMERASE ALPHA, DNA POLYMERASE DELTA, AND REPLICATION FACTOR C SUGGESTS AN ASYMMETRIC DNA POLYMERASE DIMER [J] . Maga G, Hubscher U Biochemistry . 1996,第18期

机译：DNA复制机器-包含DNA聚合酶α，DNA聚合酶δ和复制因子C的复合物的功能表征建议不对称的DNA聚合酶二聚体
4. HDX/MS of the E. coli replicative DNA polymerase identifies stabilizing interactions between the DNA sliding clamp, exonuclease and clamp loader [C] . Rafael Fernandez Leiro, Sarah L. Maslen, Meindert H. Lamers, ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：大肠杆菌复制DNA聚合酶的HDX / MS识别DNA滑动夹，外切核酸酶和夹具装载机之间的稳定相互作用
5. A group of homologous DNA replication origins and replicators dispersed throughout the human genome & Anticancer compounds targeting DNA replication initiation proteins from Chinese medicinal herbals. [D] . Wang, Ziyi. 2010

机译：一组同源的DNA复制起点和复制子，分布在整个人类基因组中，并且具有针对中草药DNA复制起始蛋白的抗癌化合物。
6. Mutations That Decrease DNA Binding of the Processivity Factor of the Herpes Simplex Virus DNA Polymerase Reduce Viral Yield Alter the Kinetics of Viral DNA Replication and Decrease the Fidelity of DNA Replication [O] . Changying Jiang, Ying T. Hwang, John C. W. Randell, 2007

机译：减少单纯疱疹病毒DNA聚合酶的合成因子的DNA结合的突变会降低病毒产量改变病毒DNA复制的动力学并降低DNA复制的保真度。
7. Mutations That Decrease DNA Binding of the Processivity Factor of the Herpes Simplex Virus DNA Polymerase Reduce Viral Yield, Alter the Kinetics of Viral DNA Replication, and Decrease the Fidelity of DNA Replication▿ [O] . Jiang, Changying, Hwang, Ying T., Randell, John C. W., 2007

机译：减少单纯疱疹病毒DNA聚合酶持续性因子的DNA结合的突变会降低病毒产量，改变病毒DNA复制的动力学并降低DNA复制的保真度▿

DNA webs-the replicators for all things tiny

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