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首页> 外文期刊>Medecine Nucleaire >Novel image derived parameters in PET/CT: Myths and reality
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Novel image derived parameters in PET/CT: Myths and reality

机译:PET / CT中新颖的图像衍生参数:神话与现实

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摘要

The role of multimodality imaging based on the use of positron emission tomography (PET) coupled to computerised tomography (CT) is continuously gaining ground in the field of oncology. The use of the technique in routine clinical practice is based on a visual interpretation or the determination of parameters such as the maximum standardised uptake value representing the highest activity voxel within the tumor. Other semi-quantitative parameters including the metabolic tumor volume and the total lesion glycolysis are increasingly used in the literature. More recently, alternative image derived parameters characterizing the tumor form and the heterogeneity in the intratumour activity distribution have been proposed. The objective of this article is to cover different aspects on these novel image derived indices, including: (i) the motivation behind their introduction and current use; (ii) obstacles in their utilization; (iii) methodological issues on their definition; (iv) their potential interest for future use in clinical practice. (C) 2015 Elsevier Masson SAS. All rights reserved.
机译:基于正电子发射断层扫描(PET)结合计算机断层扫描(CT)的多模态成像的作用在肿瘤学领域不断发展。该技术在常规临床实践中的使用基于视觉解释或确定参数(例如代表肿瘤内最高活性体素的最大标准化摄取值)。其他半定量参数,包括代谢肿瘤体积和总病变糖酵解,在文献中越来越多地使用。最近,已经提出了表征肿瘤形式和肿瘤内活性分布的异质性的替代图像衍生参数。本文的目的是涵盖这些新颖的图像衍生索引的不同方面,包括:(i)引入这些索引和当前使用的动机; (ii)使用中的障碍; (iii)关于其定义的方法问题; (iv)未来在临床实践中的潜在兴趣。 (C)2015 Elsevier Masson SAS。版权所有。

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