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Biological uptake

机译：生物吸收

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The species mangroves are consisted of Sonneratia alba, Avicen-nia marina and Avicennia alba which the dominate mangroves in Sarinah Island, Indonesia. The concentration of Pb and Cu were analyzed of roots, leaves, and sediments. This study aims on the bioaccumulation and translocation of heavy metal (Pb and Cu) in mangroves in the Sarinah Island, the ability of bioaccumulation of heavy metals in each mangrove species is provided. Uptake of the neurotoxicant monomethylmercury (MeHg) from fish and marine mammals continues to present a public health concern in Canada and elsewhere. However, fish and marine mammals are key diet items contributing to food security for some Indigenous populations in Canada. Mercury (Hg) exposure is estimated assuming that 100% of Hg is methylated, that 100% will be absorbed by the consumer and that cooking does not affect MeHg concentrations. Some of these assumptions do not correspond to our current state of knowledge. The aim of this study was to assess the impact of additional variables on Hg exposure equation using probabilistic risk analy-sis. New variables tested were (1) the proportion of methylated Hg compared to total Hg (pMeHg, %), (2) the relative absorption factor (RAF, %) expressed as bioaccessibility and (3) the mass loss factor (MLF, unitless) that represents the loss of moisture during cooking, known to increase MeHg concentration in fish and mammals. For the new variables, data from literature were used in order to set point estimate values that were further used in the probabilistic risk analysis. Modelling results for both fish and marine mammals indicate that adding these new variables significantly in-fluenced estimates of MeHg exposure (Mood's median test, p < 0.05). This study highlights that the evaluation of exposure to MeHg is sensitive to pMeHg, RAF and MLF, and the inclusion of these variables in risk assessment should be considered with care. Further research is needed to provide better food-dependent, population-specific estimates of RAF and MLF before formal inclusion in exposure estimates.
机译：品种美洲树木由Sonneratia Alba，Avicen-Nia Marina和Avicennia Alba组成，在印度尼西亚Sarinah Island中占据了红树林的统治者。分析了Pb和Cu的浓度根，叶和沉积物。本研究旨在在Sarinah岛中的红树林中的重金属（Pb和Cu）的生物累积和易位，提供每种红树林中重金属的生物累积能力。来自鱼类和海洋哺乳动物的神经毒剂单甲基汞（Mehg）的摄取仍在继续在加拿大和其他地方提出公共卫生问题。然而，鱼和海洋哺乳动物是加拿大一些土着人群的粮食安全的关键饮食项目。估计汞（Hg）曝光假设100％的Hg甲基化，100％将被消费者吸收，并且烹饪不会影响MEHG浓度。其中一些假设与我们目前的知识状态不相对应。本研究的目的是利用概率风险分析评估额外变量对Hg曝光方程的影响。测试的新变量是（1）与总Hg（PMEHg，％），（2）相对吸收因子（RAF，％）表达为生物可接受性和（3）质量损失因子（MLF，单位）的相比，甲基化Hg比例这代表了烹饪过程中水分的损失，已知在鱼和哺乳动物中增加MEHG浓度。对于新的变量，使用文献的数据以设定在概率风险分析中进一步使用的点估计值。鱼类和海洋哺乳动物的建模结果表明，将这些新的变量显着进入MEHG暴露的估计（情绪中位测试，P <0.05）。本研究强调了对MEHG暴露的评估对PMEHG，RAF和MLF敏感，并将这些变量在风险评估中纳入谨慎。在正式包含在暴露估计之前，需要进一步研究以提供更好的食物依赖性，对RAF和MLF的估计。

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    《Oceanographic Literature Review》 |2021年第4期|870-874|共5页
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