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首页> 外文期刊>Optical and quantum electronics >Determination of the kinetic parameters of glycerol diffusion in the gingival and dentinal tissue of a human tooth using optical method: in vitro studies
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Determination of the kinetic parameters of glycerol diffusion in the gingival and dentinal tissue of a human tooth using optical method: in vitro studies

机译：使用光学方法测定甘油在人牙的牙龈和牙本质组织中扩散的动力学参数：体外研究

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摘要

Due to the significant development of various optical technologies and methods used both for non-invasive diagnostics of biological tissues and for optimizing the protocols of pho-todynamic therapy, photothermal destruction, optical biopsy, tomography, etc., the problem of increasing of the light penetration depth into biological tissues is urgent, which is solved by the use of immersion agents, including hyperosmotic agents, such as glycerol. Moreover, the determination of the quantitative characteristics of the diffusion of immersion agents in biological tissues is important. In this work, we determined the effective diffusion coefficient of 99.5% glycerol in the tissue of the gingival mucosa and human dentin in vitro, which amounted to (1.78±0.28)x 10~(-6) cm~2/s (5.86±0.40)x 10~(-7) cm~2/s. The method is based on recording the kinetics of changes in the diffuse reflection spectra and applying the free diffusion model.
机译：由于用于生物组织的非侵入性诊断以及用于优化光动力疗法，光热破坏，光学活检，断层摄影等的各种光学技术和方法的显着发展，光增加的问题渗透到生物组织中的深度是紧迫的，这可以通过使用浸入剂来解决，包括高渗透剂，例如甘油。此外，确定浸没剂在生物组织中扩散的定量特征很重要。在这项工作中，我们确定了99.5％甘油在牙龈粘膜和人牙本质组织中的有效体外扩散系数，为（1.78±0.28）x 10〜（-6）cm〜2 / s（5.86± 0.40）x 10〜（-7）cm〜2 / s。该方法基于记录漫反射光谱变化的动力学并应用自由扩散模型。

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  • 来源
    《Optical and quantum electronics》 |2020年第2期|123.1-123.10|共10页
  • 作者

    A.A. Selifonov; V.V. Tuchin;

  • 作者单位

    Department of Optics and Biophotonics Saratov State University 83 Astrakhanskaya St. Saratov Russian Federation 410012 Saratov State Medical University Saratov Razumovsky B. Kazachaya 112 Russian Federation 410012;

    Department of Optics and Biophotonics Saratov State University 83 Astrakhanskaya St. Saratov Russian Federation 410012 Tomsk State University 36 Lenin Ave. Tomsk Russian Federation 634050 ITMO University Kronverksky pr. 49 St. Petersburg Russian Federation 197101 Institute of Precision Mechanics and Control Russian Academy of Sciences 24 Rabochaya st Saratov Russian Federation 410028;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Gingival tissue; Dentin; Glycerol; Molecular diffusion; Diffuse reflection spectra; Optical clearing;

    机译：牙龈组织;牙本质甘油;分子扩散漫反射光谱;光学清理;

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