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Design and analysis of graphene-MoS_2 hybrid layer based SPR biosensor with TiO_2-SiO_2 nano film for formalin detection: numerical approach

机译：基于石墨烯-MO_2杂交层的SPR型SPR型SPR型SPR生物传感器的设计与分析福尔马林检测中的纳米膜：数值方法

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摘要

In this paper, a Surface Plasmon Resonance (SPR) biosensor has been numerically developed that used Graphene-MoS2-Au-TiO2-SiO2 hybrid structure for the detection of formalin. This developed sensor has been sensed the presence the formalin based on attenuated total reflection (ATR) method by observing the change of surface plasmon resonance angle-the change of minimum reflectance attributor and the resonance frequency characteristics (RFC)-maximum transmittance attributor. Chitosan has been used as probe sensing medium to accelerate particular reaction with the formalin. Here, graphene is used as biomolecular recognition element because of its high adsorption ability and optical characteristics which helps to improve sensor sensitivity, MoS2 used for it has larger band gap, high fluroscence quenching ability, higher optical absorption efficiency, TiO2-SiO2 bilayer as the improvement of sensitivity and Gold (Au) as the sharp SPR curve. Numerical results give the impression that the variation of RFC and SPR angle for improper sensing of formalin is quiet negligible that confirms no formalin is detected whereas for proper sensing these change are considerably countable that confirms the detection of formalin. From the sensor sensitivity analysis, owing to add TiO2-SiO2 bilayer with Graphene-MoS2 Hybrid layer, maximum sensitivity of 85.375% has been numerically resulted. This high sensor performance is for taking advantages of Graphene surface high selectively which detect bio molecular compounds through pi-stacking force, larger work function (5.1eV) of MoS2 which allows the high sensitive detection of bio targets and Rich plasmon happens at the TiO2-SiO2 interface.
机译：在本文中，已经在数模上开发了表面等离子体共振（SPR）生物传感器，用于检测福尔马林的石墨烯-MOS2-AU-TiO2-SiO2混合结构。通过观察表面等离子体共振角度的变化和谐振频率特性（RFC） - 最大透射率属性的变化，已经感测了基于衰减的全反射（ATR）方法的福尔马林的存在福尔马林的存在。壳聚糖已被用作探针传感介质，以加速与福尔马林的特定反应。这里，石墨烯由于其具有高吸附能力和光学特性而用作生物分子识别元件，这有助于提高传感器灵敏度，MOS2用于其具有较大的带隙，高血管淬火能力，较高的光学吸收效率，TiO2-SiO2双层。改善敏感性和金（AU）作为锐弹簧曲线。数值结果给出了印象，即RFC和SPR角度对福尔马林的感测不正确的变化是安静的，以确认没有福尔马林被检测到，而对于正确的感应这些变化是相当数量的，证实福尔马林的检测是相当数量的。从传感器敏感性分析中，由于用石墨烯-MOS2杂交层加入TiO2-SiO2双层，最大敏感性为85.375％的数量导致。这种高传感器性能是为了通过PI堆叠力选择性地检测生物分子化合物的石墨烯表面的优点，允许MOS2的较大的功函数（5.1ev），这允许在TiO 2上发生高敏感的生物靶和富含等离子体的敏感性检测SiO2接口。

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