Design of a high numerical aperture achromatic objective lens for endomicroscopy

Mohammad Asif Zaman; Yasin Bueyuekalp

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Design of a high numerical aperture achromatic objective lens for endomicroscopy

机译：内窥镜用高数值孔径消色差物镜的设计

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An achromatic objective lens with the object-space numerical aperture (NA) of 0.7 is designed for endomicroscopy applications for in vivo diagnosis of cancer. For these applications, it is required that the size of the optical components be no more than the diameter of a biopsy needle. The challenges associated with designing such an optical system are discussed. The clear aperture size for the lens is set to 1.5 mm. The lens is achromatic for the wavelength range from 452 to 623 nm. The system was designed and optimized using CODE V optical design software. The performance of the design is analyzed and found to be within the design requirements. Tolerance analysis is also performed to check the robustness of the design.

机译：具有0.7的物距数值孔径（NA）的消色差物镜设计用于内窥镜检查应用，用于体内诊断癌症。对于这些应用，要求光学部件的尺寸不大于活检针的直径。讨论了与设计这样的光学系统相关的挑战。镜头的透明光圈尺寸设置为1.5毫米。透镜在452至623 nm的波长范围内是消色差的。该系统是使用CODE V光学设计软件进行设计和优化的。分析设计的性能，发现其在设计要求之内。还执行公差分析以检查设计的健壮性。

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来源
《Optical engineering》 |2019年第7期|075101.1-075101.9|共9页
作者
Mohammad Asif Zaman; Yasin Bueyuekalp;
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作者单位

Stanford University, Department of Electrical Engineering, Stanford, California, United States;

Stanford University, Department of Electrical Engineering, Stanford, California, United States;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);
原文格式 PDF
正文语种 eng
中图分类
关键词
achromatic; endomicroscope; lens system design; biomedical imaging; optical biopsy; cancer;

机译：消色差;元瘤病;镜头系统设计;生物医学成像;光学活检;癌症;

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专利

1. Design of a high numerical aperture achromatic objective lens for endomicroscopy [J] . Mohammad Asif Zaman, Yasin Bueyuekalp Optical engineering . 2019,第7期

机译：用于端瘤的高数值孔径无光型物镜的设计
2. Design approaches with a lenslet array and a single, high-numerical-aperture annular-field objective lens for optical data storage systems that incorporate large numbers of parallel read-write-erase channels [J] . Jose M. Sasian, Masud Mansuripur Applied optics . 1999,第7期

机译：具有小透镜阵列和单个高数值孔径环形场物镜的设计方法，用于光学数据存储系统，该系统包含大量并行读写读写通道
3. Highly Efficient Gradient Solid Immersion Lens with Large Numerical Aperture for Broadband Achromatic Deep Subwavelength Focusing and Magnified Far Field [J] . Chen Jin, Zhou Yang Yang, Chu Hong Chen, Advanced Optical Materials . 2021,第17期

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4. A novel method of lens initial structure selection: study on structures-aperture relationship of finite image distance achromatic spherical microscope objective with larger numerical aperture [C] . Liu na, Zhang Yimo, Fang Fengzhou Conference on Optical Design and Testing . 2008

机译：一种新颖的镜头初始结构选择方法：有限图像距离色球面显微镜物镜与较大数值孔径的结构 - 孔径关系研究
5. High numerical aperture injection-molded miniature objective for fiber-optic confocal reflectance microscopy. [D] . Chidley, Matthew Douglas. 2005

机译：高数值孔径的注塑微型物镜，用于光纤共聚焦反射显微镜。
6. Needle-based fluorescence endomicroscopy via structured illumination with a plastic achromatic objective [O] . Matthew Kyrish, Jessica Dobbs, Shalini Jain, 2013

机译：通过带有塑料消色差物镜的结构化照明进行基于针的荧光内窥镜检查
7. Needle-based fluorescence endomicroscopy via structured illumination with a plastic, achromatic objective [O] . Kyrish, Matthew, Dobbs, Jessica, Jain, Shalini, 2013

机译：通过带有塑料消色差物镜的结构化照明进行基于针的荧光内窥镜检查
8. Gradient Index Polymer Optics: Achromatic Singlet Lens Design [R] . Beadie, G., Fleet, E., Shirk, J. S. 2010

机译：梯度折射率聚合物光学：消色差单透镜设计

Design of a high numerical aperture achromatic objective lens for endomicroscopy

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