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Silicon nitride directional coupler interferometer for surface sensing

机译：用于表面感测的硅氮化硅定向耦合器干涉仪

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摘要

A silicon nitride directional coupler (DC) used to create ~（ab）iosensing device is presented. The DC detects changes in the refractive index of the cladding (n_(clad)) as changes in the relative output intensity. The DC length (L), nC|ad-dependent sensitivities of the DC, and preferred dimensions of the single-mode DC waveguides are obtained through numerical simulations. The performance of the DC is evaluated through end-fire coupling measurements. The intensities measured after varying the n_(C|ad )using air, water, and glycerol solutions agree well with the fitting for a wide range of L values between 60 and 600 μm, i.e., corresponding to 6 to 60 times the coupling length. The bulk refractive index sensitivity was investigated using glycerol solutions of different concentrations and was found to be 18.9 optical intensity units per refractive index unit (OIU/RIU). Biotin/streptavidin bindings were detected with a sensitivity of 60 OIU/RIU and a detection limit of 0.13 μm, suggesting the feasibility of the DC for immunosensing.
机译：呈现了用于产生〜（AB）碘化装置的氮化硅定向耦合器（DC）。 DC检测包层的折射率（n_（clad））的变化，因为相对输出强度的变化。通过数值模拟获得DC的DC长度（L），NC依赖性灵敏度和单模DC波导的优选尺寸。通过端射耦合测量评估DC的性能。在使用空气，水和甘油溶液改变N_（C | AD）之后测量的强度与拟合值的宽度范围为60至600μm，即对应于耦合长度的6至60倍。使用不同浓度的甘油溶液研究了本体折射率敏感性，并被发现为每折射率单元（OIU / RiU）的18.9光学强度单位。检测生物素/链霉抗生物素蛋白结合，其灵敏度为60 oiu / Riu和0.13μm的检出限，表明DC用于免疫溶胶的可行性。

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  • 来源
    《Optical engineering》 |2017年第1期|017101.1-017101.7|共7页
  • 作者

    Kyohei Okubo; Ken Uchiyamada; Kiyoshi Asakawa; Hiroaki Suzuki;

  • 作者单位

    University of Tsukuba Graduate School of Pure and Applied Sciences 1-1-1 Tennoudai Tsukuba Ibaraki 305-8573 Japan;

    University of Tsukuba Graduate School of Pure and Applied Sciences 1-1-1 Tennoudai Tsukuba Ibaraki 305-8573 Japan;

    University of Tsukuba Graduate School of Pure and Applied Sciences 1-1-1 Tennoudai Tsukuba Ibaraki 305-8573 Japan;

    University of Tsukuba Graduate School of Pure and Applied Sciences 1-1-1 Tennoudai Tsukuba Ibaraki 305-8573 Japan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    directional coupler; interferometry; silicon nitride waveguide; streptavidin detection;

    机译：定向耦合器;干涉测量;氮化硅波导;链霉抗生物素蛋白检测;

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