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Optical fibers for high-resolution in vivo microendoscopic fluorescence imaging

机译:用于高分辨率体内微内窥镜荧光成像的光纤

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摘要

Optical fiber-based high-resolution fluorescence imaging techniques have promising applications in clinical practice and preclinical research using animals. Here we review the instrumentation and applications of microendoscopy based on various types of optical fibers. Single-mode fibers and double-clad fibers have been widely used for delivering light from light sources to tissues and collecting light from tissues to photodetectors. Coherent fiber bundles, cylindrical graded-index lenses, and multi-mode fibers have been employed in both beam-scanning and non-scanning microscopy. With continuing advances of optical fiber technologies, further innovations in optical microendoscopy are expected.
机译:基于光纤的高分辨率荧光成像技术在动物的临床实践和临床前研究中具有广阔的应用前景。在这里,我们回顾基于各种类型的光纤的微内窥镜的仪器和应用。单模光纤和双包层光纤已被广泛用于将光从光源传递到组织,并将光从组织收集到光电探测器。相干光纤束,圆柱渐变折射率透镜和多模光纤已用于束扫描和非扫描显微镜。随着光纤技术的不断进步,有望在光学显微内窥镜领域进一步创新。

著录项

  • 来源
    《Optical fiber technology》 |2013年第6ptab期|760-771|共12页
  • 作者单位

    Department of Mechatronics, Gwangju Institute of Science and Technology, Gwangju, South Korea;

    Department of Mechatronics, Gwangju Institute of Science and Technology, Gwangju, South Korea,Department of Medical System Engineering, School of Mechatronics, Gwangju Institute of Science and Technology, Gwangju, South Korea;

    WCU Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology, Daejon, South Korea,Wellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, MA 02114, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Microendoscopy; Fluorescence imaging; Optical fiber; Fiber bundle; GRIN lens; Endomicroscopy;

    机译:显微内窥镜;荧光成像;光纤;纤维束;GRIN镜头;内镜检查;

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