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Effect of types of hydrophilic acrylic monomers in reducing glistenings of hydrophobic acrylic intraocular lenses

机译：亲水性丙烯酸类单体在减少疏水性丙烯酸眼晶状体荧光中的影响

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摘要

To reduce the glistenings in the hydrophobic acrylic intraocular lens (IOL) materials, various types of hydrophilic acrylic monomers of 2-hydroxyethyl acrylate (HEA), 2-hydroxypropyl acrylate (HPA), 4-hydroxybutyl acrylate (HBA), and 2-hydroxyethyl methacrylate (HEMA) were copolymerized with a hydrophobic acrylic monomer, 2phenoxyethyl acrylate (POEA). In this process, the effect of the types and amounts of hydrophilic acrylic monomers on the physical properties, such as glistenings, equilibrium water content (EWC), refractive index, and glass transition temperature of the resulting hydrophobic acrylic IOL materials was investigated. As the amounts of hydrophilic acrylic monomers (HEA, HPA, HBA and HEMA) increased, glistenings in the IOL materials were significantly decreased in all monomers. At the same amount of the hydrophilic acrylic monomers, the IOL materials from HEA showed the least number of glistenings, but those from HBA exhibited the largest number of glistenings, resulting in a reduction of glistenings in the following order of HEA HPA HEMA HBA. The EWCs of the IOL materials decreased in the order of HEA HPA HEMA HBA with the same amount of hydrophilic monomers. From the above results, it can be seen that the greater the degree of hydrophilicity, such as the amounts and EWCs of the hydrophilic acrylic monomers, the greater the effect of glistening reduction of the resulting IOL materials.
机译：为了减少疏水性丙烯酸眼内透镜（IOL）材料的亮光，各种类型的丙烯酸酯（HEA），2-羟丙基丙烯酸酯（HPA），4-羟基丁酯（HBA）和2-羟乙基甲酯的各种类型的亲水丙烯酸单体用疏水性丙烯酸单体，2phenOxylylate（Poea）共聚甲基丙烯酸酯（HEMA）。在该方法中，研究了所得渗透丙烯酸IOL材料的荧光丙烯酸类单体的类型和量的亲水性丙烯酸单体对物理性质的影响，例如玻璃纤维丙烯酸IOL材料的玻璃化合物，折射率和玻璃化转变温度。随着亲水性丙烯酸类单体（HEA，HPA，HBA和HEMA）的量增加，所有单体中IOL材料中的亮光显着降低。在相同量的亲水性丙烯酸单体中，来自HEA的IOL材料显示出最少数量的闪闪发光，但是来自HBA的闪闪发光亮度最多，导致亮度的亮度减少了HEA＆GT的顺序。 HPA＆ hema＆ HBA。 IOL材料的EWC在Hea＆gt的顺序下减少; HPA＆ hema＆ HBA具有相同量的亲水性单体。根据上述结果，可以看出，亲水性越大，亲水性丙烯酸类单体的含量和EWC越大，所得的IOL材料的荧光降低的效果越大。

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