Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy

Nienke Bosschaart1* Maurice C.G. Aalders1 Dirk J. Faber12 Jelmer J.A. Weda1 Martin J.C. van Gemert1 and Ton G. van Leeuwen13

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Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy

机译：低相干光谱法定量测量散射介质中的吸收光谱

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Low-coherence spectroscopy (LCS) is a spectroscopic method that allows for quantitative and localized assessment of absorption spectra by combining reflection spectroscopy with low-coherence interferometry. We describe absorption coefficient (μa)measurements by LCS in tissue simulating phantoms with varying scattering and absorbing properties. We used LCS in the 455–680 nmwavelength range with a spectral resolution of 8 nmto obtain μaspectra with ±0.5 mm−1accuracy. We conclude that LCS is a promising technique for the in vivo determination of tissue chromophore concentrations.

机译：低相干光谱法（LCS）是一种光谱方法，通过将反射光谱法与低相干干涉法相结合，可以对吸收光谱进行定量和局部评估。我们描述了LCS在模拟具有不同散射和吸收特性的体模的组织中的吸收系数（μa）测量。我们在455–680–nm波长范围内使用LCS，光谱分辨率为8 nm，以获得具有±0.5 mm-1精度的μa光谱。我们得出结论，LCS是一种用于体内确定组织发色团浓度的有前途的技术。

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《Optics Letters》 |2009年第23期|p.3746-3748|共3页
作者
Nienke Bosschaart1* Maurice C.G. Aalders1 Dirk J. Faber12 Jelmer J.A. Weda1 Martin J.C. van Gemert1 and Ton G. van Leeuwen13;
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1Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P.O. Box 22700, NL-1100 DE Amsterdam, The Netherlands 2Ophthalmology Department, Academic Medical Center, University of Amsterdam, P.O. Box 22700, NL-1100 DE Amsterdam, The Netherlands 3Biophysical Engineering Group, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente, P.O. Box 217, NL-7500 AE Enschede, The Netherlands;

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1. Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy [J] . Nienke Bosschaart, Maurice C. G. Aalders, Dirk J. Faber, Optics Letters . 2009,第23期

机译：低相干光谱法定量测量散射介质中的吸收光谱
2. Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopy [J] . Nienke Bosschaart Dirk J. Faber Ton G. van Leeuwen and Maurice C. G. Aalders journal of biomedical optics . 2011,第3期

机译：通过低相干光谱法测量与波长相关的散射和反向散射系数
3. Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopy [J] . Nienke Bosschaart, Dirk J. Faber, Ton G. vanLeeuwen, Journal of biomedical optics . 2011,第3期

机译：通过低相干光谱法测量与波长相关的散射和反向散射系数
4. Path length resolved Doppler measurements of multiple scattered photons in turbid media for various absorptions using phase modulated low-coherence interferometry [C] . Babu Varghese, Vinayakrishnan Rajan, Ton G Van Leeuwen, Biophotonics and New Therapy Frontiers; Progress in Biomedical Optics and Imaging; vol.7 no.35 . 2006

机译：使用相调制低相干干涉法对混浊介质中多种散射光子进行各种吸收的路径长度分辨多普勒测量
5. Light Scattering and Absorption Spectroscopy in Three Dimensions Using Quantitative Low Coherence Interferometry for Biomedical Applications. [D] . Robles, Francisco E. 2011

机译：使用生物医学应用中的定量低相干干涉法在三维上进行光散射和吸收光谱分析。
6. Separation of absorption and scattering properties of turbid media using relative spectrally resolved cw radiance measurements [O] . Serge Grabtchak, William M. Whelan 2012

机译：使用相对光谱分辨的连续波辐射度测量分离浑浊介质的吸收和散射特性
7. Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy [O] . Bosschaart, N., Aalders, M.C.G., Faber, D.J., 2009

机译：低相干光谱法定量测量散射介质中的吸收光谱
8. Quantitative Absorption Measurements Using Cavity-Ringdown Spectroscopy with Pulsed Lasers [R] . Looney, J. P., Hodges, R. T., van Zee, R. D. 2007

机译：使用脉冲激光的腔衰荡光谱法进行定量吸收测量

Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopy

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