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首页> 外文期刊>The Pain Clinic >Comparison of the intrauterine topical anaesthesia and paracervical block on pain in patients undergoing endometrial biopsy
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Comparison of the intrauterine topical anaesthesia and paracervical block on pain in patients undergoing endometrial biopsy

机译：子宫内膜活检患者宫腔局部麻醉和宫颈旁阻滞对疼痛的比较

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Objective: To evaluate the efficacy and safety of topical endometrial anaesthesia during endometrial biopsy and compare it with standard paracervical block. Methods: 114 women in reproductive period undergoing endometrial biopsy for abnormal uterine bleeding were enrolled into this study. Women were randomly assigned into four groups to receive different anaesthetics. Group A (placebo group) received intrauterine placebo; Group B received intrauterine lidocaine hydrochloride solution; Group C received paracervical injection of 1 : 1 diluted lidocaine solution alone and Group D received intrauterine topical anaesthesia in addition to paracervical block. All patients were asked by the nurse to rate the intensity of pain on a 0-100 mm scale (VAS) during the application of the anaesthetic (T1), cervical dilation (T2) (if needed), endometrial biopsy (T3) and 15 minutes after the procedure (T4). Results: All groups were similar in medical and demographic characteristics. The mean pain intensity scored on VAS in groups C and D was significantly higher than in groups A and B at T1 and lower at T3 and T4 (p < 0.05). On the other hand, considering only the patients who did not need cervical dilation during the procedure, there was not any significant difference on the pain experienced at T3 and T4. Conclusions: Intrauterine anaesthesia is not better than the other anesthetic techniques and has no additive effect on conventional paracervical block in reducing the pain during endometrial biopsy, but it is effective in reducing the occurrence of vasovagal reaction.
机译：目的：评价局部子宫内膜麻醉在子宫内膜活检过程中的疗效和安全性，并将其与标准宫颈旁阻滞进行比较。方法：本研究纳入了114例处于生育期的子宫内膜异位活检妇女。将妇女随机分为四组，接受不同的麻醉剂。 A组（安慰剂组）接受宫内安慰剂； B组接受宫内注射盐酸利多卡因溶液治疗； C组仅接受宫颈旁注射1：1稀释的利多卡因溶液，D组除接受宫颈旁阻滞外，还接受宫内局部麻醉。护士要求所有患者在应用麻醉剂（T1），子宫颈扩张术（T2）（如果需要），子宫内膜活检（T3）和15时在0-100毫米范围（VAS）上评估疼痛的强度手术后（T4）分钟。结果：所有组的医学和人口统计学特征均相似。 C组和D组在VAS上评分的平均疼痛强度在T1时显着高于A和B组，在T3和T4时较低（p <0.05）。另一方面，仅考虑在手术过程中不需要宫颈扩张的患者，在T3和T4时所经历的疼痛没有任何显着差异。结论：宫内麻醉并不比其他麻醉技术更好，并且在减少子宫内膜活检过程中的疼痛方面对常规子宫颈旁阻滞没有附加作用，但可有效减少血管迷走反应的发生。

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