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Performance of the Pulmonary Autograft in Four Infants After the Ross Procedure

机译：Ross手术后四名婴儿的肺自体移植的性能

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摘要

Pulmonary valve autografts have proven to be valid aortic valve substitutes in children. The objective of this study is to evaluate the performance of the pulmonary autograft (PAG) in systemic position and its adjustment to growth in four infants who underwent a Ross operation. Between April 1998 and January 2000, four infants whose aortic valve anatomy and function were judged unsuitable for a valve-sparing operation underwent successful Ross operation. All patients were followed postoperatively with echocardiograms to evaluate the function and the dimensional changes of the PAG within the systemic circulation. The PAG adjustments to growth were compared to the growth of the pulmonary root of healthy patients matched for body surface area, with the purpose to evaluate the effects of the systemic pressure on the pulmonary vascular wall, as a passive dilatation process versus a true and active structural adaptation. Median follow-up was 53 months (range, 48–65). There were no early deaths or reoperations. All patients were asymptomatic and in stable hemodynamic conditions. The PAG annulus grew according to body surface area without dilatation. PAG valve regurgitation was present but mild in three patients. Trans-PAG peak gradients were not significant. The PAG diameter at the level of the sinuses of Valsalva and sinotubular junction increased rapidly and steadily in all patients during follow-up compared to controls.
机译：肺动脉瓣自体移植物已被证明是儿童有效的主动脉瓣替代物。这项研究的目的是评估肺自体移植（PAG）在全身位置的性能以及其对接受Ross手术的四名婴儿的生长状况的调节。在1998年4月至2000年1月之间，四名主动脉瓣解剖结构和功能均被认为不适合保留瓣膜的婴儿接受了成功的Ross手术。所有患者术后均进行超声心动图检查，以评估体循环内PAG的功能和尺寸变化。将PAG对生长的调整与匹配于体表面积的健康患者肺根的生长进行比较，目的是评估全身压力对肺血管壁的影响，作为被动扩张过程与真实主动过程的比较结构适应。中位随访时间为53个月（范围48-65）。没有早期死亡或再次手术。所有患者无症状且血液动力学稳定。 PAG环根据身体表面积生长而无扩张。存在PAG瓣膜反流，但三例患者轻度。 Trans-PAG峰梯度不明显。与对照组相比，所有患者在随访过程中所有患者的窦房和窦管交界处的PAG直径均迅速且稳定地增加。

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  • 来源
    《Pediatric Cardiology》 |2005年第6期|797-800|共4页
  • 作者

    V.L. Vida; M. Rubino; T. Bottio; S. Sponga; O. Milanesi; G. Stellin;

  • 作者单位

    Department of Pediatric Cardiac Surgery University of Padova Medical School;

    Department of Pediatric Cardiac Surgery University of Padova Medical School;

    Department of Pediatric Cardiac Surgery University of Padova Medical School;

    Department of Pediatric Cardiac Surgery University of Padova Medical School;

    Department of Pediatric Cardiology University of Padova Medical School;

    Department of Pediatric Cardiac Surgery University of Padova Medical School;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    Infant; Pulmonary autograft; Echocardiography;

    机译：婴儿;肺自体移植;超声心动图;

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