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Impaired Poststenotic Aortic Pulsatility After Hemodynamically Ideal Coarctation Repair in Children

机译:血液动力学理想的缩窄修复后的儿童后狭窄主动脉搏动受损。

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Using echocardiographic quantification of aortic pulsatility distal to the site of the surgical anastomosis, we evaluated whether the preoperatively impaired poststenotic aortic pulsatility returned to normal after repair of coarctation with a hemodynamically ideal result. Patients who underwent repair of aortic coarctation without residual obstruction were compared to a matched group of normal children. A standardized M-mode echocardiographic evaluation of the aorta at the diaphragmatic level was performed for all patients. Measurements consisted of maximum and minimum aortic diameters, time intervals, and a calculated pulsatility index. Compared to normal children (n = 19), 20 children with operated coarctation and with a hemodynamically ideal result showed a significantly smaller increase in aortic diameter in systole (mean of 29 ± 7% in patients versus 37 ± 7% in normals; p < 0.01). In contrast to patients with coarctation in whom the maximum aortic distension is reached much later during the cardiac cycle, hemodynamically normalized, operated patients in our study had no such delay (maximum aortic pulsation at 28% of cardiac cycle time compared to 27% in normals; p = not significant). The pulsatility index of the poststenotic aorta was clearly lower in operated children (mean, 130 ± 50%/sec) compared to a normal mean value of 202 ± 33%/sec but was still significantly higher than that in patients with unoperated coarctation, who showed a low mean value of 51 ± 24%/sec (p < 0.01). After correction of aortic coarctation with a hemodynamically ideal result, the pulsatility of the poststenotic aorta, severely impaired prior to repair, did not return to normal during the observation period in the patients studied.
机译:使用超声心动图量化手术吻合术远端远端的主动脉搏动,我们评估了缩窄修复后的血液动力学理想结果,术前受损的狭窄后主动脉搏动是否恢复正常。将接受主动脉缩窄修复而无残余阻塞的患者与正常儿童的配对组进行比较。对所有患者均进行了横standardized水平主动脉的标准化M型超声心动图评估。测量包括最大和最小主动脉直径,时间间隔以及计算出的搏动指数。与正常儿童(n = 19)相比,有20例经手术矫正并具有血液动力学理想结果的儿童显示主动脉缩径的增大明显较小(患者的平均值为29±7%,而正常人的平均值为37±7%; p < 0.01)。与缩窄的患者在心动周期中达到最大主动脉扩张的时间相反,本研究中经血流动力学正常化,手术的患者没有这种延迟(最大的主动脉搏动在心动周期的28%,而正常人为27%) ; p =不重要)。与正常平均值202±33%/ sec相比,接受手术的儿童的狭窄后主动脉搏动指数明显较低(平均130±50%/ sec),但仍显着高于未经手术的缩窄患者(后者)。显示出51±24%/ sec的低平均值(p <0.01)。在校正具有血液动力学理想结果的主动脉缩窄后,研究对象患者在修复前严重受损的后狭窄主动脉的搏动在观察期内未恢复正常。

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