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首页> 外文期刊>Pediatric Cardiology >Systematic-to-Pulmonary Collaterals: A Source of Flow Energy Loss in Fontan Physiology
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Systematic-to-Pulmonary Collaterals: A Source of Flow Energy Loss in Fontan Physiology

机译：系统到肺的抵押品：丰坦生理学中流动能量损失的来源

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摘要

Patients with Fontan-modified, single-ventricle heart frequently have systemic collaterals that increase pulmonary blood flow. Competitive flow from these auxiliary vessels can also elevate pulmonary artery pressure, a process leading to erosion of flow’s mechanical energy. An analogous analytical description of mixing fluid streams was used to provide insight into flow energetics associated with systemic-to-pulmonary collaterals in Fontan-type circulation. We find that theoretical pressure increases and flow energy losses due to mixing vary quadratically as the velocity differences of the interacting fluid streams. Moreover, the predicted flow energy loss is shown to depend directly on the resultant pressure increase. Based on studies of aortopulmonary collaterals in patients with Fontan anatomy, we provide an estimate of pulmonary artery pressure elevation and flow energy loss, factors that are of considerable clinical importance.
机译：具有Fontan修饰的单心室心脏的患者经常具有全身性的侧支，可增加肺血流量。这些辅助血管产生的竞争性流量也会升高肺动脉压力，这一过程导致流量的机械能受到侵蚀。混合流体流的类似分析描述用于深入了解Fontan型循环中与系统到肺侧支相关的流能。我们发现理论压力增加，并且由于混合而导致的流能损失随着相互作用的流体流的速度差而平方变化。而且，预测的流动能量损失显示为直接取决于最终的压力增加。基于对Fontan解剖患者的主肺旁支的研究，我们提供了对肺动脉压力升高和血流能量损失的估计，这些因素在临床上具有重要意义。

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