Theoretical Prediction of a Phase Diagram for Solid Dispersions

Bin Tian; Xiaoyan Wang; Yuanyuan Zhang; Keru Zhang; Yu Zhang; Xing Tang

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Theoretical Prediction of a Phase Diagram for Solid Dispersions

机译：固体分散体相图的理论预测

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Purpose To predict the temperature-composition phase diagram of solid dispersions (SDs) through theoretical approaches using cinnarizine-Soluplus® SD as a model system and evaluate the predicted results.

机译：目的通过理论方法，以肉桂那嗪-Soluplus®SD为模型系统，预测固体分散体（SD）的温度组成相图，并评估预测结果。

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《Pharmaceutical Research》 |2015年第3期|840-851|共12页
作者
Bin Tian; Xiaoyan Wang; Yuanyuan Zhang; Keru Zhang; Yu Zhang; Xing Tang;
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Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

Department of Pharmaceutics Science Shenyang Pharmaceutical University">(1);

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1. Theoretical Prediction of a Phase Diagram for Solid Dispersions [J] . Tian Bin, Wang Xiaoyan, Zhang Yuanyuan, Pharmaceutical research . 2015,第3期

机译：固体分散体相图的理论预测
2. Prediction of the thermal phase diagram of amorphous solid dispersions by Flory-Huggins theory. [J] . Zhao Y, Inbar P, Chokshi HP, Journal of pharmaceutical sciences. . 2011,第8期

机译：用Flory-Huggins理论预测非晶态固体分散体的热相图。
3. Construction of drug-polymer thermodynamic phase diagrams using flory-huggins interaction theory: Identifying the relevance of temperature and drug weight fraction to phase separation within solid dispersions [J] . Molecular pharmaceutics . 2013,第1期

机译：使用弗洛尔-哈金斯相互作用理论构建药物-聚合物热力学相图：鉴定温度和药物重量分数与固体分散体中相分离的相关性
4. CONSTRUCTION OF A PHASE DIAGRAM FOR ITRACONAZOLE/EC 20 CPS SOLID DISPERSIONS PREPARED BY HOT STAGE EXTRUSION WITH AND WITHOUT INJECTION OF PRESSURIZED CO_2 [C] . Geert Verreck, Annelies Decorte, Liesbeth Theunissen, European Meeting on Supercritical Fluids Reactions, Materials and Natural Products Processing . 2005

机译：用热级挤出制备的伊唑唑/ EC 20 CPS固体分散体的构建型号，无需注入加压CO_2
5. Theoretical investigations of the phase diagram of solid magnesium. [D] . Althoff, Jeffrey David. 1992

机译：固体镁相图的理论研究。
6. Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory–Huggins Theory [O] . Krishna Bansal, Uttam Singh Baghel, Seema Thakral 2016

机译：基于弗洛里-哈金斯理论的非晶态固体分散体二元相图的构建和验证
7. Construction and Validation of Binary Phase Diagram for Amorphous Solid Dispersion Using Flory–Huggins Theory [O] . Krishna Bansal, Uttam Singh Baghel, Seema Thakral 2015

机译：使用福伦 - Huggins理论的无定形牢固分散二元相图的构建与验证
8. Theoretical phase diagrams for solid H(sub 2). [R] . Surh, M. P., Runge, K. J. 1993

机译：固体H（sub 2）的理论相图。

Theoretical Prediction of a Phase Diagram for Solid Dispersions

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