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首页> 外文期刊>Pharmaceutical Research >A Photo-Activated Targeting Chemotherapy Using Glutathione Sensitive Camptothecin-Loaded Polymeric Micelles
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A Photo-Activated Targeting Chemotherapy Using Glutathione Sensitive Camptothecin-Loaded Polymeric Micelles

机译:使用谷胱甘肽敏感喜树碱加载的聚合物胶束的光激活靶向化疗。

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Purpose A novel photo-activated targeted chemotherapy was developed by photochemical internalization (PCI) of glutathione-sensitive polymeric micelles incorporating camptothecin (CPT) prepared from thiolated CPT (CPT-DP) and thiolated poly(ethylene glycol)-b-poly(glutamic acid) (PEG-b-P(Glu-DP))
机译:目的通过对谷胱甘肽敏感性聚合物胶束的光化学内在化(PCI)并入由喜树碱(CPT)制备的新型光活化靶向化学疗法,喜树碱(CPT)由硫醇化CPT(CPT-DP)和硫醇化聚(乙二醇)-b-聚谷氨酸制成)(PEG-bP(Glu-DP))

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