Contrast-Enhanced MRI-Guided Photodynamic Cancer Therapy with a Pegylated Bifunctional Polymer Conjugate

Anagha Vaidya; Yongen Sun; Yi Feng; Lyska Emerson; Eun-Kee Jeong; Zheng-Rong Lu

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Contrast-Enhanced MRI-Guided Photodynamic Cancer Therapy with a Pegylated Bifunctional Polymer Conjugate

机译：聚乙二醇化双功能聚合物偶联物增强MRI引导的光动力癌症治疗

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摘要

To study contrast-enhanced MRI guided photodynamic therapy with a pegylated bifunctional polymer conjugate containing an MRI contrast agent and a photosensitizer for minimally invasive image-guided cancer treatment.

机译：要研究使用聚乙二醇化双功能聚合物共轭物（包含MRI造影剂和光敏剂）的造影增强MRI引导的光动力疗法，以进行微创图像引导的癌症治疗。

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来源
《Pharmaceutical Research》 |2008年第9期|2002-2011|共10页
作者
Anagha Vaidya; Yongen Sun; Yi Feng; Lyska Emerson; Eun-Kee Jeong; Zheng-Rong Lu;
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作者单位

Department of Pharmaceutics and Pharmaceutical Chemistry University of Utah Salt Lake City Utah 84112 USA;

Department of Pharmaceutics and Pharmaceutical Chemistry University of Utah Salt Lake City Utah 84112 USA;

Department of Pharmaceutics and Pharmaceutical Chemistry University of Utah Salt Lake City Utah 84112 USA;

Department of Pathology University of Utah Salt Lake City Utah 84112 USA;

Department of Radiology University of Utah Salt Lake City Utah 84112 USA;

Department of Pharmaceutics and Pharmaceutical Chemistry University of Utah Salt Lake City Utah 84112 USA;

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原文格式 PDF
正文语种 eng
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关键词
dynamic contrast enhanced MRI; image-guided cancer therapy; non-invasive pharmacokinetics; photodynamic therapy; polymer conjugates;

机译：动态对比增强MRI;图像引导的癌症治疗;无创药代动力学;光动力治疗;聚合物结合物;

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专利

1. Contrast-enhanced MRI-guided photodynamic cancer therapy with a pegylated bifunctional polymer conjugate. [J] . Vaidya A, Sun Y, Feng Y, Pharmaceutical research . 2008,第9期

机译：对比增强的MRI引导光动力癌疗法用聚乙二醇化双官能聚合物缀合物治疗。
2. A Cancer-Recognizing Polymeric Photosensitizer Based on the Tumor Extracellular pH Response of Conjugated Polymers for Targeted Cancer Photodynamic Therapy~a [J] . Songhee Jeong, Wooram Park, Chung-Sung Lee, Macromolecular bioscience . 2014,第12期

机译：基于共轭聚合物肿瘤细胞pH反应的可识别癌症的聚合光敏剂，用于靶向光动力疗法〜a
3. PEGylated N-(2 hydroxypropyl) methacrylamide-doxorubicin conjugate as pH-responsive polymeric nanoparticles for cancer therapy [J] . Bobde Yamini, Biswas Swati, Ghosh Balaram Reactive & Functional Polymers . 2020,第Juna期

机译：聚乙二醇化的N-（2羟丙基）甲基丙烯酰胺 - 多柔比星缀合物作为pH响应聚合物纳米粒子用于癌症治疗
4. A PEGylated Polymer-Photosensitizer Conjugate Containing Gd (Ⅲ) for Site-Specific MRI-guided Photodynamic Therapy of Cancer [C] . Anagha Vaidya, Yong-En Sun, Yi Feng, Controlled Release Society Annual Meeting and Exposition . 2007

机译：含Gd（Ⅲ）的PEG化聚合物光敏剂偶联物用于特定部位的MRI指导的光动力疗法
5. Bifunctional polymeric conjugates for contrast-enhanced magnetic resonance imaging-guided noninvasive photodynamic therapy of cancer. [D] . Vaidya, Anagha Mahadeo. 2008

机译：用于对比增强磁共振成像引导的非侵入性光动力疗法的双功能聚合物共轭物。
6. Contrast-enhanced MRI-guided photodynamic cancer therapy with a pegylated bifunctional polymer conjugate [O] . Anagha Vaidya, Yongen Sun, Yi Feng, -1

机译：聚乙二醇化双功能聚合物偶联物增强MRI引导的光动力癌症治疗
7. Design of Bifunctional Dendritic 5-Aminolevulinic Acid and Hydroxypyridinone Conjugates for Photodynamic Therapy [O] . Tao Zhou, Sinan Battah, Francesca Mazzacuva, 2018

机译：用于光动力疗法的双官能树突5-氨基乙酸和羟基吡啶酮缀合物的设计
8. Targetable Polymer-Antiangiogenic Drug Conjugates for Systemic Breast Cancer Therapy [R] . Nan, A. 2006

机译：用于系统性乳腺癌治疗的可靶向聚合物 - 抗血管生成药物偶联物

Contrast-Enhanced MRI-Guided Photodynamic Cancer Therapy with a Pegylated Bifunctional Polymer Conjugate

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