ATR/Raman and Fractal Characterization of HPBCD/Progesterone Complex Solid Particles

Adamo Fini; Francesca Ospitali; Giorgio Zoppetti; Nadia Puppini

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ATR/Raman and Fractal Characterization of HPBCD/Progesterone Complex Solid Particles

机译：HPBCD /孕酮复合固体颗粒的ATR /拉曼和分形表征

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摘要

Characterization of hydroxypropyl-β-cyclodextrin/progesterone (HPBCD/P) complex solid particles obtained from an aqueous solution, by three different technological processes, with the aim of preparing ready-to-dissolve powders for injectable as well as solid oral formulations in progestinic therapy.

机译：通过三种不同的工艺方法，对从水溶液中获得的羟丙基-β-环糊精/孕酮（HPBCD / P）复合固体颗粒进行表征，目的是制备用于孕激素的可注射和固体口服制剂的易溶粉末治疗。

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来源
《Pharmaceutical Research》 |2008年第9期|2030-2040|共11页
作者
Adamo Fini; Francesca Ospitali; Giorgio Zoppetti; Nadia Puppini;
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作者单位

Dipartimento SMETEC University of Bologna Via San Donato 15 40127 Bologna Italy;

Dipartimento di Chimica Fisica e Inorganica University of Bologna Bologna Italy;

IBSA Institut Biochimique Lugano Switzerland;

IBSA Institut Biochimique Lugano Switzerland;

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原文格式 PDF
正文语种 eng
中图分类
关键词
dissolution; image analysis; Progesterone/HPBCD complex solid particles; Raman and FT-IR spectra;

机译：溶解度;图像分析;孕酮/ HPBCD复合固体颗粒;拉曼光谱和红外光谱;

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专利

1. ATR/Raman and fractal characterization of HPBCD/progesterone complex solid particles. [J] . Fini A, Ospitali F, Zoppetti G, Pharmaceutical research . 2008,第9期

机译：HPBCD /孕酮复合固体颗粒的ATR /拉曼光谱和分形特征。
2. Solid state characterization of progesterone in a freeze dried 1:2 progesterone/HPBCD mixture. [J] . Zoppetti G, Puppini N, Ospitali F, Journal of pharmaceutical sciences. . 2007,第7期

机译：冷冻干燥的1：2孕酮/ HPBCD混合物中孕酮的固态表征。
3. Characterization of Raman Scattering in Solid Samples with Different Particle Sizes and Elucidation on the Trends of Particle Size-Dependent Intensity Variations in Relation to Changes in the Sizes of Laser Illumination and Detection Area [J] . Pham K. Duy, Seulah Chun, Hoeil Chung Analytical chemistry . 2017,第22期

机译：不同粒度尺寸的固体样品中拉曼散射的特征及阐明粒度依赖性强度变化的趋势与激光照射和检测区域大小的变化
4. Nondestructive characterization of nanoparticles in solids by Raman spectroscopy and small angle x-ray scattering [C] . M. Herms, G. Irmer, P. Verma, Testing, Reliability, and Application of Micro- and Nano-Material Systems III . 2005

机译：拉曼光谱和小角度X射线散射对固体中纳米颗粒的无损表征
5. Polymer-assisted photogeneration of metal nanoparticles in fluids and within elastic solid matrices: Characterization, mechanism of formation and direct photopatterning. [D] . Korchev, Andriy S. 2005

机译：流体和弹性固体基质中金属纳米粒子的聚合物辅助光生成：表征，形成机理和直接光图案化。
6. Solid-state characterization studies and effect of PEG 20000 and P90G on particle size reduction and stability of complexed glimepiride nanocrystals [O] . Babasahib Sajeev Kumar, Raman Saraswathi, Sokkalingam Arumugham Dhanaraj 2013

机译：固态表征研究以及PEG 20000和P90G对复合格列美脲纳米晶体的粒径减小和稳定性的影响
7. Synthesis and characterizations of NiO nanoparticles via solid-state thermal decomposition of nickel(II) Schiff base complexes [O] . 2014

机译：Ni（II）Schiff碱配合物的固态热分解法合成NiO纳米粒子及其表征
8. Solid State Raman Materials Characterization and Raman Shifting Of 1.3 Micron Laser Radiation. [R] . 2000

机译：1.3微米激光辐射的固态拉曼材料表征和拉曼漂移。

ATR/Raman and Fractal Characterization of HPBCD/Progesterone Complex Solid Particles

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