Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

Shirou Itagaki; Elangovan Gopal; Lina Zhuang; You-Jun Fei; Seiji Miyauchi; Puttur D. Prasad; Vadivel Ganapathy

首页> 外文期刊>Pharmaceutical Research >Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

【24h】

Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

机译：布洛芬和其他结构相关的NSAID与钠偶联的单羧酸盐转运蛋白SMCT1（SLC5A8）的相互作用

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Sodium-coupled monocarboxylate transporter 1 (SMCT1) is a Na+-coupled transporter for monocarboxylates. Many nonsteroidal anti-inflammatory drugs (NSAIDs) are monocarboxylates. Therefore, we investigated the interaction of these drugs with human SMCT1 (hSMCT1).

机译：钠偶联单羧酸盐转运蛋白1（SMCT1）是Na +偶联的单羧酸盐转运蛋白。许多非甾体抗炎药（NSAIDs）是单羧酸盐。因此，我们研究了这些药物与人SMCT1（hSMCT1）的相互作用。

著录项

来源
《Pharmaceutical Research》 |2006年第6期|1209-1216|共8页
作者
Shirou Itagaki; Elangovan Gopal; Lina Zhuang; You-Jun Fei; Seiji Miyauchi; Puttur D. Prasad; Vadivel Ganapathy;
展开▼
作者单位

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

Department of Biochemistry and Molecular Biology Medical College of Georgia Augusta Georgia 30912 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词
blocker; electrophysiology; ibuprofen; sodium dependence; SMCT1;

机译：阻断剂;电生理学;布洛芬;钠依赖性;SMCT1;

相似文献

外文文献
中文文献
专利

1. Interaction of ibuprofen and other structurally related NSAIDs with the sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8). [J] . Itagaki S, Gopal E, Zhuang L, Pharmaceutical research . 2006,第6期

机译：布洛芬和其他与结构相关的NSAID与钠偶联的单羧酸盐转运蛋白SMCT1（SLC5A8）的相互作用。
2. Identification of the multivalent PDZ protein PDZK1 as a binding partner of sodium-coupled monocarboxylate transporter SMCT1 (SLC5A8) and SMCT2 (SLC5A12) [J] . Srivastava Sunena, Nakagawa Kiyoshi, He Xin, The journal of physiological sciences: JPS . 2019,第2期

机译：鉴定多价PDZ蛋白PDZK1作为钠偶联单羧酸钠转运蛋白SMCT1（SLC5A8）和SMCT2的结合配偶体（SMCT2）
3. Expression of the Sodium-Coupled Monocarboxylate Transporters SMCT1 (SLC5A8) and SMCT2 (SLC5A12) in Retina. [J] . Martin PM, Dun Y, Mysona B, Investigative ophthalmology & visual science . 2007,第7期

机译：钠耦合的单羧酸盐转运蛋白SMCT1（SLC5A8）和SMCT2（SLC5A12）在视网膜中的表达。
4. Incorporation of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Poly(propylene) Matrices for Wound Healing Applications. The case of Ibuprofen [C] . Argyrios N. Nochos, Christos Kontoyannis, George G. Voyiatzis Hellenic Polymer Society Conference on New Polymeric Materials Applications . 2013

机译：掺入非甾体抗炎药（NSAID）在伤口愈合应用中的聚（丙烯）基质中。布洛芬的案例
5. Three Dimensional Homology Modeling of Organic Cation Transporter 3 to Identify Structural Elements Mediating Transporter-Substrate Interactions. [D] . Liu, Hebing. 2017

机译：有机阳离子转运蛋白3的三维同源性建模，以识别介导转运蛋白-底物相互作用的结构元素。
6. Insulin and SGK1 reduce the function of Na+/monocarboxylate transporter 1 (SMCT1/SLC5A8) [O] . Adriana López-Barradas, Tania González-Cid, Norma Vázquez, -1

机译：胰岛素和SGK1降低Na + /单羧酸盐转运蛋白1（SMCT1 / SLC5A8）的功能
7. Protein-Protein Interaction between Sodium-Coupled Monocarboxylate Transporter 1 (SMCT1) and PDZ Domain-Containing Ring Finger Domain 3 (PDZRN3) [O] . Yusuke Otsuka 2017

机译：钠偶联单羧酸酯转运蛋白转运蛋白（SMCT1）和含PDZ结构域的无胶指结构域3的蛋白质 - 蛋白质相互作用（PDZRN3）

Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8)

摘要

著录项

相似文献

相关主题

期刊订阅