Photodynamic therapeutic efficacy of symmetrical diiodinated squaraine in in vivo skin cancer models

Soumya M. S.; Devi D. Gayathri; Shafeekh K. M.; Das Suresh; Abraham Annie

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Photodynamic therapeutic efficacy of symmetrical diiodinated squaraine in in vivo skin cancer models

机译：对称二碘化方酸在体内皮肤癌模型中的光动力治疗功效

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Background: Photodynamic therapy (PDT) has clinical approval for use as a minimally invasive therapeutic procedure that is able to exert selective cytotoxic activity toward malignant cells. The dye selected for our study, symmetrical diiodinated squaraine, is one of the newly developed photosensitizers. The study is designed to determine the efficacy of PDT mediated by symmetrical diiodinated squaraine in skin tumor induced Swiss albino mice.

机译：背景：光动力疗法（PDT）已获得临床认可，可用作微创治疗程序，能够对恶性细胞发挥选择性细胞毒活性。为我们的研究选择的染料，对称的二碘化方酸，是新开发的光敏剂之一。该研究旨在确定对称二碘化方酸介导的PDT在皮肤肿瘤诱导的瑞士白化病小鼠中的功效。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2017年第6期|302-309|共8页
作者
Soumya M. S.; Devi D. Gayathri; Shafeekh K. M.; Das Suresh; Abraham Annie;
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作者单位

Univ Kerala, Dept Biochem, Kariavattom Campus, Trivandrum 695581, Kerala, India;

Univ Kerala, Dept Biochem, Kariavattom Campus, Trivandrum 695581, Kerala, India;

CSIR, NIIST, Chem Sci & Technol Div, Photosci & Photon Sect, Ind Estate PO, Trivandrum 695019, Kerala, India;

CSIR, NIIST, Chem Sci & Technol Div, Photosci & Photon Sect, Ind Estate PO, Trivandrum 695019, Kerala, India;

Univ Kerala, Dept Biochem, Kariavattom Campus, Trivandrum 695581, Kerala, India;

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正文语种 eng
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Photodynamic therapy; Symmetrical diiodinated squaraine; Swiss albino mice; Skin tumor; Tumor markers; Apoptosis;

机译：光动力疗法;对称二碘代方酸;瑞士白化病小鼠;皮肤肿瘤;肿瘤标志物;细胞凋亡;

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1. Bis(3,5-diiodo-2,4,6-trihydroxyphenyl)squaraine: A novel candidate in photodynamic therapy for skin cancer models in vivo [J] . D. Gayathri Devi, T.R. Cibin, D. Ramaiah Journal of Photochemistry and Photobiology, B. Biology: Official Journal of the European Society for Photobiology . 2008,第3期

机译：Bis（3,5-diiodo-2,4,6-trihydroxyphenyl）squaraine：体内皮肤癌模型光动力疗法的新型候选药物
2. Liposomal CpG-ODN: An in vitro and in vivo study on macrophage subtypes responses, biodistribution and subsequent therapeutic efficacy in mice models of cancers [J] . Nikoofal-Sahlabadi Sara, Riahi Maryam Matbou, Sadri Kayvan, European journal of pharmaceutical sciences . 2018,第期

机译：脂质体CPG-ODN：体外和体内研究癌症癌模型中的巨噬细胞亚型反应，生物分布和随后的治疗效果
3. Talaporfin-mediated photodynamic therapy for peritoneal metastasis of gastric cancer in an in vivo mouse model: Drug distribution and efficacy studies [J] . Kentaro Kishi, Masahiko Yano, Masahiro Inoue, International journal of oncology . 2010,第2期

机译：塔拉泊芬介导的光动力疗法在体内小鼠模型中治疗胃癌腹膜转移的研究：药物分布和功效研究
4. In Vivo Small Animal Imaging for Early Assessment of Therapeutic Efficacy of Photodynamic Therapy for Prostate Cancer [C] . Baowei Fei, Hesheng Wang, Xiang Chen, Conference on Medical Imaging 2007: Physiology, Function, and Structure from Medical Images pt.1 . 2006

机译：体内小动物成像，早期评估光动力疗法治疗前列腺癌的疗效
5. Investigations of the biodistribution and phototherapeutic utility of two palladium(II)-containing macrocyclic drugs in a tumour-bearing mouse model: A study of the pharmacokinetics and tissue distribution of the potential photodynamic drug palladium-bacteriopheophorbide as well as the in vivo treatment efficacy and tissue distribution of the potential photothermal drug palladium(II) octabutoxynaphthalocyanine. [D] . DeGroot, Jennifer Leanne. 2002

机译：两种含钯（II）的大环药物在荷瘤小鼠模型中的生物分布和光疗实用性的研究：潜在的光动力药物钯-细菌脱镁叶绿酸的药代动力学和组织分布以及体内治疗效果和研究光热药物钯（II）八丁氧基萘酞菁的组织分布。
6. Topical calcitriol prior to photodynamic therapy enhances treatment efficacy in non-melanoma skin cancer mouse models [O] . Kishore Rollakanti, Sanjay Anand, Edward V. Maytin -1

机译：光动力疗法前的局部骨化三醇可增强非黑色素瘤皮肤癌小鼠模型的治疗功效
7. In vivo small animal imaging for early assessment of therapeutic efficacy of photodynamic therapy for prostate cancer [O] . Baowei Fei, Hesheng Wang, Xiang Chen, 2007

机译：用于早期评估前列腺癌光动力疗法治疗疗效的体内小动物成像

Photodynamic therapeutic efficacy of symmetrical diiodinated squaraine in in vivo skin cancer models

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