Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma

Castilho-Fernandes Andrielle; Lopes Tacila G.; Primo Fernando L.; Pinto Marcelo R.; Tedesco Antonio C.

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Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma

机译：氯铝酞菁纳米乳液诱导胶质母细胞瘤的光动力学过程

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Background: Glioblastoma multiforme (GBM) is a tumor characterized by rapid cell proliferation and migration. GBM constitutes the most aggressive and deadly type of brain tumor and is classified into several subtypes that show high resistance to conventional therapies. There are currently no curative treatments for malignant glioma despite the numerous advances in surgical techniques, radiotherapy, and chemotherapy. Therefore, alternative approaches are required to improve GBM treatment.

机译：背景：多形性胶质母细胞瘤（GBM）是一种以细胞快速增殖和迁移为特征的肿瘤。 GBM构成了脑肿瘤中最具侵害性和致命性的类型，被分类为对常规疗法表现出高度抵抗力的几种亚型。尽管外科手术技术，放射疗法和化学疗法取得了许多进步，但目前尚无用于治疗恶性神经胶质瘤的治疗方法。因此，需要替代方法来改善GBM治疗。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2017年第9期|221-228|共8页
作者
Castilho-Fernandes Andrielle; Lopes Tacila G.; Primo Fernando L.; Pinto Marcelo R.; Tedesco Antonio C.;
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作者单位

Univ Sao Paulo, Ctr Nanotechnol & Tissue Engn Photobiol & Photome, Dept Chem, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP, Brazil;

Univ Sao Paulo, Ctr Nanotechnol & Tissue Engn Photobiol & Photome, Dept Chem, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP, Brazil;

Univ Sao Paulo, Ctr Nanotechnol & Tissue Engn Photobiol & Photome, Dept Chem, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP, Brazil;

Univ Sao Paulo, Ctr Nanotechnol & Tissue Engn Photobiol & Photome, Dept Chem, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP, Brazil;

Univ Sao Paulo, Ctr Nanotechnol & Tissue Engn Photobiol & Photome, Dept Chem, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP, Brazil;

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正文语种 eng
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关键词
Glioblastoma multiforme (GBM); Glioma; Photodynamic therapy (PDT); Aluminum chloride phthalocyanine (AlClPc);

机译：胶质母细胞瘤（GBM）;胶质瘤;光动力疗法（PDT）;氯化铝酞菁（AlClPc）;

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1. Effects of photodynamic therapy mediated by nanoemulsion containing chloro-aluminum phthalocyanine: a histologic and immunohistochemical study in human gingiva [J] . de Moraes Maiara, Vasconcelos Roseane Carvalho, Figueiro Longo Joao Paulo, Photodiagnosis and Photodynamic Therapy . 2015,第4期

机译：含氯铝酞菁纳米乳介导的光动力疗法的作用：人牙龈的组织学和免疫组化研究
2. Evaluation of a chloroaluminium phthalocyanine-loaded magnetic nanoemulsion as a drug delivery device to treat glioblastoma using hyperthermia and photodynamic therapy [J] . L. B. de Paula, F. L. Primo, M. R. Pinto, RSC Advances . 2017,第15期

机译：评估使用氯铝酞菁磁性纳米乳剂作为药物治疗装置的热疗和光动力疗法，以治疗胶质母细胞瘤
3. Development, characterization, and in vitro trials of chloroaluminum phthalocyanine-magnetic nanoemulsion to hyperthermia and photodynamic therapies on glioblastoma as a biological model [J] . L. B. de Paula, F. L. Primo, D. R. Jardim, Journal of Applied Physics . 2012,第7pta2期

机译：氯铝酞菁磁性纳米乳剂对胶质母细胞瘤的热疗和光动力疗法的生物学模型的开发，表征和体外试验
4. (07B307) Development, characterization, and in vitro trials of chloroaluminum phthalocyanine-magnetic nanoemulsion to hyperthermia and photodynamic therapies on glioblastoma as a biological model [C] . L. B. de Paula, F. L Primo, D. R. Jardim Annual Conference on Magnetism and Magnetic Materials . 2012

机译：（07b307）氯铝酞菁 - 磁性纳米乳液对胶质母细胞瘤的热疗和光动力疗法的开发，表征和体外试验作为生物学模型
5. Biological activities of phthalocyanines: Effects of human serum components on the in vitro uptake and photodynamic activity of zinc phthalocyanine. [D] . Obochi, Modestus O. K. 1992

机译：酞菁的生物活性：人血清成分对锌酞菁的体外吸收和光动力活性的影响。
6. Nanoemulsions with Chloroaluminium Phthalocyanine and Paromomycin for Combined Photodynamic and Antibiotic Therapy for Cutaneous Leishmaniasis [O] . Sandra Milena Leal Pinto, Luis Alexandre Muehlmann, Lucía Liliana Mantilla Ojeda, 2021

机译：用氯铝氰基氰胺和乳腺霉素组合光动力学和抗生素治疗的纳米乳蛋白皮肤嗜血液和抗生素治疗
7. Aluminium-phthalocyanine chloride nanoemulsions for anticancer photodynamic therapy: Development and in vitro activity against monolayers and spheroids of human mammary adenocarcinoma MCF-7 cells [O] . Luis Alexandre Muehlmann, Mosar Corrêa Rodrigues, João Paulo Figueiró Longo, 2015

机译：铝-酞菁氯化物纳米乳剂用于抗癌光动力疗法：对人乳腺腺癌细胞MCF-7细胞的单层和球状体的形成和体外活性

Photodynamic process induced by chloro-aluminum phthalocyanine nanoemulsion in glioblastoma

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