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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Novel strategy in giant cutaneous squamous cell carcinoma treatment: The case experience with a combination of photodynamic therapy and surgery
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Novel strategy in giant cutaneous squamous cell carcinoma treatment: The case experience with a combination of photodynamic therapy and surgery

机译：巨大皮肤鳞状细胞癌治疗的新策略：光动力疗法与手术相结合的案例经验

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摘要

The treatment for giant cutaneous squamous cell carcinoma (cSCC) is challenging. Here, we reported that a 90 year-old patient with giant cSCC was successfully treated through combination of surgery and photodynamic therapy (PDT). Due to the advanced patient age, large tumor area, and deep infiltration, radical surgery cannot be performed initially. After in situ resection, five rounds of topical 5-aminolevulinic acid PDT were continuously performed. The surgical wound was healed five months after resection. Seven months after initial resection, the residual tumor was resected by a radical surgery. The patient was followed up for six months after the radical surgical resection and showed no tumor recurrence. This case suggested that initial utmost resection for main body of tumor, decreasing the tumor boundary by PDT treatment and the sequential treatment regimen of radical surgery can be an effective therapeutic schedule for refractory and giant cSCC.
机译：巨大的皮肤鳞状细胞癌（cSCC）的治疗具有挑战性。在这里，我们报道了通过外科手术和光动力疗法（PDT）的组合成功治疗了90岁的巨型cSCC患者。由于患者年龄高，肿瘤面积大和浸润深，最初无法进行根治性手术。原位切除后，连续进行五轮局部5-氨基乙酰丙酸PDT。手术伤口在切除五个月后he愈。最初切除后七个月，通过根治性手术切除残留的肿瘤。根治性手术切除后对患者进行了六个月的随访，未见肿瘤复发。该病例提示，首先对肿瘤主体进行最大程度的切除，通过PDT治疗缩小肿瘤边界，以及根治性手术的序贯治疗方案，可以成为难治性和巨大cSCC的有效治疗方案。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2017年第9期|116-118|共3页
  • 作者

    Bu Wenbo; Wang Yan; Chen Xu; Fang Fang;

  • 作者单位

    Chinese Acad Med Sci, Inst Dermatol, Jiangsu Key Labo Ratory Mol Biol Skin Dis & STIs, Nanjing 210042, Jiangsu, Peoples R China;

    Chinese Acad Med Sci, Inst Dermatol, Jiangsu Key Labo Ratory Mol Biol Skin Dis & STIs, Nanjing 210042, Jiangsu, Peoples R China;

    Chinese Acad Med Sci, Inst Dermatol, Jiangsu Key Labo Ratory Mol Biol Skin Dis & STIs, Nanjing 210042, Jiangsu, Peoples R China;

    Chinese Acad Med Sci, Inst Dermatol, Jiangsu Key Labo Ratory Mol Biol Skin Dis & STIs, Nanjing 210042, Jiangsu, Peoples R China;

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  • 正文语种 eng
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  • 关键词

    cutaneous squamous cell carcinoma; surgery; photodynamic therapy;

    机译：皮肤鳞状细胞癌;手术;光动力疗法;

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