• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Experience and BCC subtypes as determinants of MAL-PDT response: Preliminary results of a national Brazilian project
【24h】

Experience and BCC subtypes as determinants of MAL-PDT response: Preliminary results of a national Brazilian project

机译：经验和BCC亚型是MAL-PDT反应的决定因素：巴西国家级项目的初步结果

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Non-melanoma skin cancer is the most prevalent cancer type in Brazil and worldwide. Photodynamic therapy (PDT) is a noninvasive technique with excellent cosmetic outcome and good curative results, when used for the initial stages of skin cancer. A Brazilian program was established to determine the efficacy of methyl aminolevulinate (MAL)-PDT, using Brazilian device and drug. The equipment is a dual device that combines the photodiagnosis, based on widefield fluorescence, and the treatment at 630 nm. A protocol was defined for the treatment of basal cell carcinoma with 20% MAL. cream application. The program also involves the training of the medical teams at different Brazilian regions, and with distinct facilities and previous PDT education. In this report we present the partial results of 27 centers with 366 treated BCC lesions in 294 patients. A complete response (CR) was observed in 76.5% (280/366). The better response was observed for superficial BCC, with CR 160 lesions (80.4%), when compared with nodular or pigmented BCC. Experienced centers presented CR of 85.8% and 90.6% for superficial and nodular BCC respectively. A high influence of the previous doctor experience on the CR values was observed, especially due to a better tumor selection.
机译：非黑色素瘤皮肤癌是巴西和全世界最普遍的癌症类型。当用于皮肤癌的初始阶段时，光动力疗法（PDT）是一种非侵入性技术，具有出色的美容效果和良好的治疗效果。建立了巴西程序，使用巴西装置和药物确定氨基乙酰丙酸甲酯（MAL）-PDT的功效。该设备是一个双重设备，结合了基于宽场荧光的光诊断和630 nm的处理。定义了用20％MAL治疗基底细胞癌的方案。奶油应用。该计划还包括对巴西不同地区的医疗团队进行培训，并配备不同的设施和先前的PDT教育。在这份报告中，我们介绍了294例患者中27个中心的366例BCC病灶的部分结果。在76.5％（280/366）中观察到完全缓解（CR）。与结节性或有色性BCC相比，浅表BCC的CR 160病变（80.4％）观察到更好的反应。经验丰富的中心对浅表和结节性BCC的CR分别为85.8％和90.6％。观察到以前的医生经验对CR值有很大的影响，特别是由于更好的肿瘤选择。

著录项

  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2014年第1期|22-26|共5页
  • 作者

    Dora P. Ramirez; Cristina Kurachi; Natalia M. lnada; Lilian T. Moriyama; Ana G. Salvio; Jose D. Vollet Filho; Layla Pires; Hilde H. Buzza; Cintia Teles de Andrade; Clovis Greco; Vanderlei S. Bagnato;

  • 作者单位

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Skin Department, Amaral Carvalho Foundation, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

    Biophotonics Laboratory, Sao Carlos Institute of Physics, University of Sao Paulo (USP), 13566-590 Sao Carlos, Sao Paulo, Brazil;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Non-melanoma skin cancer; Photodynamic therapy; National Brazilian project; BCC subtypes; Doctor experience; Determinants;

    机译：非黑色素瘤皮肤癌;光动力疗法;巴西国家项目;BCC亚型;医生经验;行列式;

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号