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What is the role of photodynamic therapy in the treatment of acne vulgaris?

机译:光动力疗法在寻常痤疮的治疗中起什么作用?

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Despite the efficacy of oral retinoids and antibiotics in the treatment of acne vulgaris, there remains the need for additional treatment options for selected patient groups such as those who are resistant, intolerant or unable to take conventional therapies. Improvement of acne vulgaris with visible light phototherapy is well documented [1,2] and although the mechanism of action is unclear it is likely that anti-inflammatory, immunomodulatory and endogenous photodynamic therapy (PDT) effects are operative. However the place of PDT using exogenous photosensitisation in the treatment of acne requires clarification. In a Pubmed search of acne and PDT, 200 relevant articles were identified demonstrating the growing interest in this area.
机译:尽管口服类维生素A和抗生素在寻常痤疮的治疗中有效,但仍需要针对某些患者群体(例如耐药,不耐受或无法采取常规疗法的患者)提供其他治疗选择。可见光疗法可改善寻常痤疮[1,2],尽管作用机理尚不清楚,但抗炎,免疫调节和内源性光动力疗法(PDT)的作用仍可能起作用。但是,PDT在治疗痤疮中使用外源光敏剂的位置需要澄清。在痤疮和PDT的Pubmed搜索中,发现了200篇相关文章,表明对该领域的兴趣日益浓厚。

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