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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Salvage PDT for persistent esophageal cancer after chemoradiotherapy
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Salvage PDT for persistent esophageal cancer after chemoradiotherapy

机译：放疗后挽救PDT用于持续性食管癌

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Despite recent epidemiologic trends in North America and Europe, esophageal cancer is still a relatively uncommon tumor. Consequently no single centre is likely to accrue sufficient numbers of patients with all stages of esophageal malignancy to make definitive recommendations for management. The report by Wolfsen and Hemminger therefore evaluates a highly selected patient population, seven patients only, who were judged to be medically unfit for potentially curative surgery after induction chemoradiotherapy, and who were found to have persistent or recurrent esophageal carcinoma. The encouraging results achieved following salvage photodynamic therapy (PDT), specifically in terms of control of local disease in the five patients with adenocarcinoma, warrant further careful evaluation and future study to define the role of this innovative approach to treat recurrent or recalcitrant esophageal malignancy.
机译：尽管在北美和欧洲最近流行病学趋势，食管癌仍是一种相对罕见的肿瘤。因此，没有哪个中心可以招募到足够多的食管恶性肿瘤所有阶段的患者来提出明确的治疗建议。因此，Wolfsen和Hemminger的报告评估了高度选择的患者人群，仅七名患者，这些患者被认为在诱导放化疗后在医学上不适合进行潜在的手术治疗，并且被发现患有顽固性或复发性食管癌。挽救性光动力疗法（PDT）之后取得的令人鼓舞的结果，特别是在控制5例腺癌患者的局部疾病方面，值得进一步仔细评估和进一步研究，以定义这种创新方法在治疗复发或顽固性食管恶性肿瘤中的作用。

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