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Clinical study on hemoporfin PDT for infant facial port-wine stains

机译：血红素PDT治疗婴儿面部口红酒斑的临床研究

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摘要

Objective: To observe the clinical efficacy and therapeutic response of Hemoporfin photodynamic therapy (PDT) for infant facial port-wine stains (PWS).Method: Hemoporfin PDT was used to treat 100 cases of infant facial PWS. After receiving Hemoporfin skin test, the cases with a negative skin test result were intravenously injected with Hemippofen (5 mg/kg) and irradiated under 532 nm LED green light. After treatment, a follow-up visit was paid through WeChat and Dermlink PWS consulting platform, in order to observe the therapeutic response and clinical efficacy.Result The follow-up visit showed an effective rate of 98%, including 85 cases of itching (85%), 100 cases of edema (100%), 89 cases of purpura-like change (89%), 33 cases of crust (33%), 2 cases of hyperpigmentation (2%) and 2 cases of scars (2%), with no allergy and other systematic adverse reaction.Conclusion: Hemoporfin PDT has a high clinical efficacy and response rate in treating infant facial PWS, with slight adverse reactions.
机译：目的：观察血红素光动力疗法（PDT）治疗婴儿面部口红酒斑（PWS）的临床疗效和治疗效果。方法：以血红素PDT治疗婴儿面部PWS 100例。接受Hemoporfin皮肤测试后，对皮肤测试结果阴性的患者静脉注射Hemippofen（5 mg / kg），并在532 nm LED绿光下照射。治疗后，通过微信和Dermlink PWS咨询平台进行随访，观察疗效和临床疗效。结果随访表明，瘙痒有效率为98％，其中瘙痒85例（85例）。 ％），100例水肿（100％），89例紫癜样变化（89％），33例硬皮（33％），2例色素沉着（2％）和2例疤痕（2％）结论：血卟啉PDT在治疗婴儿面部PWS中具有较高的临床疗效和反应率，且不良反应较轻。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2019年第3期|106-110|共5页
  • 作者

    Zhang Yunjie; Yang Yuguang; Zhang Zhe; Yang Yanjin; Qiu Meng; Chen Hongxia; Li Lei; Zou Xianbiao;

  • 作者单位

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

    Peoples Liberat Army Gen Hosp, Affiliated Hosp 1, Dept Dermatol, Beijing 100048, Peoples R China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Hemoporfin; PDT; Infant; PWS; Port wine stains;

    机译：血卟啉;PDT;婴儿;PWS;波特酒渍;

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