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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >The capability and potential of new forms of personalized colon cancer treatment: Immunotherapy and Photodynamic Therapy
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The capability and potential of new forms of personalized colon cancer treatment: Immunotherapy and Photodynamic Therapy

机译：新型个性化结肠癌治疗的能力和潜力：免疫疗法和光动力疗法

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摘要

Introduction: PDT can interfere with cytokine-mediated responses that play an important role in the processes of cancer progression, tumor angiogenesis and metastasis. Therefore, based on the identification of these cancer biomarkers, the therapy of combining various forms of treatment, including immunotherapy and PDT, may be a justified strategy for colorectal cancer treatment that focuses on individualized comprehensive therapy.Method: We reviewed the major approaches on the use of immunotherapy in colorectal cancer, with the special regard to photodynamic therapy, its immunological effect and new oncological treatment directions, connected with adjuvant immunotherapy including use of nanoparticles. Databases such as PubMed, ScienceDirect and Springer were utilized to search the literature for relevant articles.Purpose: To review studies of the immunotherapy in colon cancer and immune response to PDT.Conclusion: Based on the identification of immunological cancer biomarkers, the therapy of combining various forms of treatment, including immunotherapy and PDT, may be a justified strategy for colorectal cancer treatment that focuses on individualized comprehensive therapy.
机译：简介：PDT可以干扰细胞因子介导的反应，这些反应在癌症进展，肿瘤血管生成和转移过程中起着重要作用。因此，基于这些癌症生物标志物的识别，结合免疫治疗和PDT等多种治疗形式的疗法可能是针对个体化综合疗法的结直肠癌治疗的合理策略。免疫疗法在大肠癌中的应用，特别是光动力学疗法，其免疫学作用和新的肿瘤学治疗方向，与包括纳米颗粒在内的辅助免疫疗法有关。目的：综述结肠癌免疫疗法和对PDT免疫反应的研究。结论：基于免疫学生物标志物的鉴定，联合治疗包括免疫治疗和PDT在内的各种治疗形式可能是针对个体化综合治疗的结直肠癌治疗的合理策略。

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  • 来源
    《Photodiagnosis and Photodynamic Therapy》 |2019年第3期|253-258|共6页
  • 作者

    Kaleta-Richter Marta; Kawczyk-Krupka Aleksandra; Aebisher David; Bartusik-Aebisher Dorota; Czuba Zenon; Cieslar Grzegorz;

  • 作者单位

    Med Univ Silesia, Ctr Laser Diagnost & Therapy, Dept Internal Dis Angiol & Phys Med, Sch Med,Div Dent Zabrze, Batorego St 15, PL-41902 Bytom, Poland|Med Univ Silesia, Dept Internal Med Dermatol & Allergol, Sch Med, Div Dent Zabrze, Marii Curie Sklodowskiej St 10, PL-41800 Zabrze, Poland;

    Med Univ Silesia, Ctr Laser Diagnost & Therapy, Dept Internal Dis Angiol & Phys Med, Sch Med,Div Dent Zabrze, Batorego St 15, PL-41902 Bytom, Poland;

    Univ Rzeszow, Fac Med, Dept Photomed & Phys Chem, Tadeusza Rejtana Ave 16 C, PL-35310 Rzeszow, Poland;

    Univ Rzeszow, Fac Med, Dept Biochem & Gen Chem, Tadeusza Rejtana Ave 16 C, PL-35310 Rzeszow, Poland;

    Med Univ Silesia, Dept Microbiol & Immunol, Sch Med, Div Dent Zabrze, 19 Jordana St, PL-41808 Zabrze, Poland;

    Med Univ Silesia, Ctr Laser Diagnost & Therapy, Dept Internal Dis Angiol & Phys Med, Sch Med,Div Dent Zabrze, Batorego St 15, PL-41902 Bytom, Poland;

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  • 正文语种 eng
  • 中图分类
  • 关键词

    Colorectal cancer; Cytokines; Immunotherapy; Photodynamic therapy;

    机译：大肠癌;细胞因子;免疫疗法;光动力疗法;

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