ALA-PDT combined with holmium laser therapy of postoperative recurrent extramammary Paget's disease

Li Chunxiao; Guo Lehang; Wang Peiru; Shi Lei; Sun Xiaofei; Hu Chan; Zhang Guolong; Zhang Linglin; Zhang Yunfeng; Wang Xiuli

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ALA-PDT combined with holmium laser therapy of postoperative recurrent extramammary Paget's disease

机译：ALA-PDT联合激光治疗术后复发性乳房外Paget病

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摘要

Extramammary Paget's disease (EMPD) is a rare intraepithelial neoplasm arising in apocrine rich area of the skin. Surgery is the standard treatment but relapse is common. The postoperative skin defects, penile reconstruction, functional effects and old age are also challenges for curing disease. Herein, a case of postoperative recurrent EMPD, which was treated by combination therapy of non-invasive repeatable ALA-PDT and deep penetrated holmium laser is reported. Ultrasonography monitor of lesions showed light vascularity and the formerly hypoechoic lesion disappeared after treatment.

机译：乳腺Paget病（EMPD）是一种罕见的上皮内肿瘤，发生在皮肤上分泌丰富的区域。手术是标准治疗方法，但复发很常见。术后皮肤缺损，阴茎重建，功能作用和衰老也是治愈疾病的挑战。在此，报道了通过非侵入性可重复ALA-PDT和深穿透deep激光的联合疗法治疗的术后复发性EMPD病例。病变的超声检查仪显示血管轻度，治疗后先前的低回声病变消失。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2019年第9期|92-94|共3页
作者
Li Chunxiao; Guo Lehang; Wang Peiru; Shi Lei; Sun Xiaofei; Hu Chan; Zhang Guolong; Zhang Linglin; Zhang Yunfeng; Wang Xiuli;
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作者单位

Tongji Univ Shanghai Skin Dis Hosp Inst Photomed Sch Med 1278 Baode Rd Shanghai 200443 Peoples R China;

Tongji Univ Shanghai Peoples Hosp 10 Ultrasound Res & Educ Inst Dept Med Ultrasound Sch Med Shanghai Peoples R China;

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正文语种 eng
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关键词
Extramammary Paget's disease; ALA-photodynamic therapy; Holmium laser; Ultrasonography;

机译：乳腺Paget病;ALA光动力疗法;laser激光;超声检查;

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专利

1. ALA-PDT combined with holmium laser therapy of postoperative recurrent extramammary Paget's disease [J] . Li Chunxiao, Guo Lehang, Wang Peiru, Photodiagnosis and Photodynamic Therapy . 2019,第SEPa期

机译：ALA-PDT联合激光治疗术后复发性乳房外Paget病
2. Postoperative radiation therapy for extramammary Paget's disease [J] . Hata M., Koike I., Wada H., British Journal of Dermatology . 2015,第4期

机译：乳房外Paget病的术后放射治疗
3. A pilot study of topical imiquimod therapy for the treatment of recurrent extramammary Paget's disease [J] . Cowan Renee A., Black Destin R., Hoang Lien N., Gynecologic Oncology: An International Journal . 2016,第1期

机译：局部咪喹莫特疗法治疗复发性乳房外Paget病的初步研究
4. Using Electromagnetic Microwave Field Combined With Laserotherapy in Postoperative Period of Patients With Purulent-Inflammatory Diseases of the Hand in Outpatient Clinic [C] . L. Rabenok, V. Grimalsky, D. Juarez-R. Mexican Symposium on Medical Physics . 2008

机译：使用电磁微波场与激光疗法联合在术后诊所的尿液炎症疾病患者术后疗法
5. Second Generation Cardiac Cell Therapy: Combining Cardiac Stem Cells and Circulating Angiogenic Cells for the Treatment of Ischemic Heart Disease. [D] . Latham, Nicholas. 2013

机译：第二代心脏细胞疗法：结合心脏干细胞和循环血管生成细胞治疗缺血性心脏病。
6. A PILOT STUDY OF TOPICAL IMIQUIMOD THERAPY FOR THE TREATMENT OF RECURRENT EXTRAMAMMARY PAGETS DISEASE [O] . Renee A. Cowan, Destin R. Black, Lien N. Hoang, -1

机译：咪喹莫特治疗复发性乳腺上皮疾病的初步研究
7. A pilot study of topical imiquimod therapy for the treatment of recurrent extramammary Paget's disease [O] . Renee A. Cowan, Destin R. Black, Lien N. Hoang, 2016

机译：局部咪喹氏疗法治疗复发性肾形腺疾病的试验研究

ALA-PDT combined with holmium laser therapy of postoperative recurrent extramammary Paget's disease

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