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首页> 外文期刊>Photodiagnosis and Photodynamic Therapy >Evaluation of changes in choroidal vascularity during acute anterior uveitis attack in patients with ankylosing spondylitis by using binarization of EDI-optical coherence tomography images
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Evaluation of changes in choroidal vascularity during acute anterior uveitis attack in patients with ankylosing spondylitis by using binarization of EDI-optical coherence tomography images

机译：利用EDI光相干断层扫描图像二值化急性前静脉炎患者急性前静脉膜炎患者急性前葡萄炎患者的变化评价

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Background: To evaluate the effect of the first acute anterior uveitis (AAU) attack on the choroid by using an image binarization tool on images from enhanced depth imaging (EDI)-optical coherence tomography (OCT) scans in patients with ankylosing spondylitis (AS).Methods: In this study, three groups were formed: uveitic eyes (UE; n = 20) of patients with AS, the non-uveitic eyes (NUE; n = 20) of these patients, and the eyes of healthy controls (n = 20). EDI-OCT images were obtained during the first AAU attack and at three months after treatment in patients with AS. An image binarization tool (ImageJ software; Bethesda, MD USA) was used on EDI-OCT images to determine choroidal structures. Choroidal vascularity index (CVI) was defined as the ratio of luminal area to total subfoveal choroidal area.Results: Compared to the convalescent period, CVI was found to be significantly increased in UE (63.2 +/- 2.87 vs. 60.9 +/- 5.2 %, p = 0.045) and NUE (63.8 +/- 5.67 vs. 61.5 +/- 4.3 %, p = 0.039), while stromal area (SA) was found to be significantly reduced only in UE (0.487 +/- 0.19 vs. 0.569 +/- 0.18, p = 0.012) in the attack period.Conclusions: Changes in the CVI values of UE and NUE groups in the first AAU attack shows that there is underlying choroidal inflammation in patients with AS. It also seems that SA is the most affected choroidal structure in eyes suffering from an attack. The present study revealed that CVI measurements can be used for follow-up and the determination of treatment response in AS patients with AAU attack.
机译：背景：通过在高度增强的深度成像（EDI） - 光度相干断层扫描（OCT）扫描中的图像二值化工具在强直性脊柱炎（AS）中的图像（ECT）扫描（AS）中的图像二值化工具，评估第一急性前葡萄膜炎（AAU）对脉络膜的影响。方法：在这项研究中，形成了三组：患者（NUE; n = 20）的患者的患者（UE; n = 20），以及健康对照的眼睛（n = 20）。在第一次AAU攻击期间获得EDI-OCT图像，并在患者治疗后三个月获得。在EDI-OCT图像上使用了图像二值化工具（Imagej软件; Bethesda，MD USA）以确定脉络膜结构。脉络膜血管性指数（CVI）被定义为腔面积与总子流域的比率。结果：与临时期相比，UE中的CVI显着增加（63.2 +/- 2.87与60.9 +/- 5.2 ％，p = 0.045）和nue（63.8 +/- 5.67与61.5 +/- 4.3％，p = 0.039），而在UE中发现基质区域（SA）显着降低（0.487 +/- 0.19 Vs 。在攻击时期0.569 +/- 0.18，p = 0.012）。结论：第一个AAU攻击中UE和NUE组的CVI值的变化表明，患者患有潜在的脉络膜炎症。似乎SA也是患有攻击的眼睛中受影响最大的脉络膜结构。本研究表明，随着AAU攻击患者的患者，CVI测量可用于随访和测定治疗反应的治疗反应。

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