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Theoretical study and simulation of light-addressable potentiometric sensors

机译:光寻址电位传感器的理论研究与仿真

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摘要

The light-addressable potentiometric sensor (LAPS) is a semiconductor-based potentiometric sensor using a light probe with an ability of detecting the concentration of biochemical species in a spatially resolved manner. As an important biomedical sensor, research has been conducted to improve its performance, for instance, to realize high-speed measurement. In this work, the idea of facilitating the device-level simulation, instead of using an equivalent-circuit model, is presented for detailed analysis and optimization of the performance of the LAPS. Both carrier distribution and photocurrent response have been simulated to provide new insight into both amplitude-mode and phase-mode operations of the LAPS. Various device parameters can be examined to effectively design and optimize the LAPS structures and setups for enhanced performance. Distribution of minority carriers inside a Si-based LAPS structure under illumination with different wavelengths.
机译:光寻址电位传感器(LAPS)是基于半导体的电位传感器,它使用光探针,能够以空间分辨的方式检测生化物质的浓度。作为重要的生物医学传感器,已经进行了研究以提高其性能,例如实现高速测量。在这项工作中,提出了简化设备级仿真的想法,而不是使用等效电路模型,以详细分析和优化LAPS的性能。已经对载流子分布和光电流响应进行了仿真,以提供关于LAPS的幅度模式和相位模式操作的新见解。可以检查各种设备参数,以有效地设计和优化LAPS结构和设置,以提高性能。硅基LAPS结构内不同波长照明下少数载流子的分布。

著录项

  • 来源
    《Physica status solidi》 |2014年第6期|1467-1472|共6页
  • 作者单位

    Department of Electronic Engineering, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan;

    Department of Electronic Engineering, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan;

    Institute of Nano- and Biotechnologies (INB), Aachen University of Applied Sciences, Heinrich-Mussmannstr. 1,52428 Juelich, Germany;

    Institute of Nano- and Biotechnologies (INB), Aachen University of Applied Sciences, Heinrich-Mussmannstr. 1,52428 Juelich, Germany;

    Department of Electronic Engineering, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan,Department of Biomedical Engineering, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai 980-8577, Japan;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    biosensors; device simulations; light-addressable potentiometric sensors;

    机译:生物传感器设备仿真;光寻址电位传感器;

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