Stress-Dependent Elasticity of Composite Actin Networks as a Model for Cell Behavior

M. L. Gardel; F. Nakamura; J. Hartwig; J. C. Crocker; T. P. Stossel; D. A. Weitz

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Stress-Dependent Elasticity of Composite Actin Networks as a Model for Cell Behavior

机译：复合肌动蛋白网络的应力依赖性弹性作为细胞行为的模型

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Networks of filamentous actin cross-linked with the actin-binding protein filamin A exhibit remarkable strain stiffening leading to an increase in differential elastic modulus by several orders of magnitude over the linear value. The variation of the frequency dependence of the differential elastic and loss moduli as a function of prestress is consistent with that observed in living cells, suggesting that cell elasticity is always measured in the nonlinear regime, and that prestress is an essential control parameter.

机译：与肌动蛋白结合蛋白丝素A交联的丝状肌动蛋白网络显示出显着的应变变硬，导致差分弹性模量比线性值增加了几个数量级。微分弹性模量和损耗模量的频率依赖性作为预应力的函数变化与在活细胞中观察到的一致，表明细胞弹性总是在非线性状态下测量，预应力是必不可少的控制参数。

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来源
《Physical review letters》 |2006年第8期|p.088102.1-088102.4|共4页
作者
M. L. Gardel; F. Nakamura; J. Hartwig; J. C. Crocker; T. P. Stossel; D. A. Weitz;
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Department of Physics and D.E.A.S., Harvard University, Cambridge, Massachusetts 02138, USA;

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原文格式 PDF
正文语种 eng
中图分类物理学;
关键词
filaments; microtubules; their networks; and supramolecular assemblies; linear viscoelasticity; mechanical properties;

机译：细丝微管;他们的网络;及超分子组装;线性粘弹性;力学性能;

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1. Measurement and computer modeling of temporary arrangements of polygonal actin structures in trabecular meshwork cells which consist of cross-linked actin networks and polygonal actin arrangements [J] . ZhengY., CurrieL., PollockN., Journal of ocular pharmacology and therapeutics: The official journal of the Association for Ocular Pharmacology and Therapeutics . 2014,第2a3期

机译：小梁网状细胞中多边形肌动蛋白结构的临时排列的测量和计算机建模，该结构由交联的肌动蛋白网络和多边形肌动蛋白排列组成
2. Using neural networks to modeling the transverse elasticity modulus of unidirectional composites [J] . Eduardo Cesar Bezerra Camara, Raimundo Carlos Silverio Freire Jr Composites . 2011,第7期

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3. AUXINS AND CYTOKININS AS ANTIPODAL MODULATORS OF ELASTICITY WITHIN THE ACTIN NETWORK OF PLANT CELLS [J] . Grabski S., Schindler M. Plant physiology . 1996,第3期

机译：Auxins和细胞分裂素作为植物细胞ACTIN网络中弹性的前体调节剂
4. Prediction of stress-strain behavior of ceramic matrix composites using unit cell model [C] . Takuya Suzuki, Yasuhiro Ohtake, Yoshihiro Otani, Workshop on Testing and Modeling Ceramic and Carbon Matrix Composites . 2016

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5. Composite Fading Channel Modeling and Information Capacity of Distributed Antenna Architectures in Cellular Networks. [D] . Al-Ahmadi, Saad. 2010

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6. Auxins and Cytokinins as Antipodal Modulators of Elasticity within the Actin Network of Plant Cells. [O] . S. Grabski, M. Schindler 1996

机译：生长素和细胞分裂素是植物细胞肌动蛋白网络内弹性的对映调节剂。
7. Stress-Dependent Elasticity of Composite Actin Networks as a Model for Cell Behavior [O] . Gardel, M. L, Nakamura, F., Hartwig, J., 2006

机译：复合肌动蛋白网络的应力依赖性弹性作为细胞行为的模型
8. Cell model for homogenization of fiber-reinforced composites: General theory and nonlinear elasticity effects [R] . Aidun, J. B. , Addessio, F. L. 1995

机译：纤维增强复合材料均匀化的细胞模型：一般理论和非线性弹性效应

Stress-Dependent Elasticity of Composite Actin Networks as a Model for Cell Behavior

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