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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Can amino acid requirements for nutritional maintenance in adult humans be approximated from the amino acid composition of body mixed proteins?
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Can amino acid requirements for nutritional maintenance in adult humans be approximated from the amino acid composition of body mixed proteins?

机译：可以从人体混合蛋白质的氨基酸组成中近似得出成年人营养维持所需的氨基酸吗？

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摘要

The quantitative needs for the dietary indispensable amino acids in adult human protein nutrition are still poorly established. Tracer studies with 13C-labeled amino acids have been undertaken previously in our laboratories to reevaluate and further determine the minimum physiological needs for selected indispensable amino acids in healthy adult volunteers. For those amino acids that have not yet been studied by this approach we have proposed a tentative set of requirement figures based on considerations of the amino acid composition of body mixed proteins and the rate of obligatory amino acid losses (i.e., losses when the diet contains no proteins or amino acids). Here we provide an argument for, and a justification of, this approach as an interim measure until more comprehensive data become available on the quantitative aspects of amino acid metabolism in healthy humans.
机译：成人蛋白质营养中饮食中不可缺少的氨基酸的定量需求仍未建立。我们实验室以前曾进行过13C标记氨基酸的示踪剂研究，以重新评估并进一步确定健康成人志愿者中所选必不可少的氨基酸的最低生理需求。对于尚未通过这种方法研究过的那些氨基酸，我们基于人体混合蛋白质的氨基酸组成和必需氨基酸损失率（即，饮食中含没有蛋白质或氨基酸）。在此，我们为这种方法作为一种临时措施提供了论据和理由，直到获得有关健康人体内氨基酸代谢的定量方面的更全面的数据为止。

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