The in situ spatial arrangement of the influenza A virus matrix protein M1 assessed by tritium bombardment

ALEXANDER V. SHISHKOV; VITALII I. GOLDANSKII; LUDMILA A. BARATOVA

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The in situ spatial arrangement of the influenza A virus matrix protein M1 assessed by tritium bombardment

机译：用tri轰击评估甲型流感病毒基质蛋白M1的原位空间排列

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摘要

Intact influenza A virions were bombarded with thermally activated tritium atoms and the intramolecular distribution of the label in the matrix protein M1 was analyzed to determine the in situ accessibility of its tryptic fragments. These data were combined with the previously reported X-ray crystal structure of the M1 fragment 2-158 [Sha,B& luo, M.(1997) nat.Struct. Biol. 4,239-244] and the predicted topology of the C domain (159-252) to propose a model of M1 arrangement in the virus particle.

机译：用热活化的atoms原子轰击完整的甲型流感病毒粒子，并分析基质蛋白M1中标记物的分子内分布，以确定其胰蛋白酶消化片段的原位可及性。这些数据与先前报道的M1片段2-158的X射线晶体结构相结合[Sha，B＆luo，M。（1997）nat.Struct。生物学[4239-244]和C结构域的预测拓扑（159-252）以提出病毒颗粒中M1排列的模型。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1999年第14期|7827-7830|共4页
作者
ALEXANDER V. SHISHKOV; VITALII I. GOLDANSKII; LUDMILA A. BARATOVA;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词
tritium planigraphy; athree-dimensional modeling; topology; secondary structure prediction.;

机译：plan平面三维建模拓扑二级结构预测。;

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1. Tritium planigraphy: Differences in the spatial structures of the influenza virus M1 protein in crystal, solution, and virion [J] . E. N. Bogacheva, A. A. Dolgov, A. L. Chulichkov, Russian journal of bioorganic chemistry . 2012,第1期

机译：t平面图：晶体，溶液和病毒粒子中流感病毒M1蛋白的空间结构差异
2. The In Situ Structural Characterization of the Influenza A Virus Matrix M1 Protein within a Virion [J] . Alexander V. Shishkov Elena N. Bogacheva Alexey A. Dolgov Alexey L. Chulichkov Denis G. Knyazev Natalia V. Fedorova Alexander L. Ksenofontov Larisa V. Kordyukova Elena V. Lukashina Vladimir M. Mirsky Lyudmila A. Baratova Protein and Peptide Letters . 2009,第11期

机译：病毒粒子内甲型流感病毒基质M1蛋白的原位结构表征
3. Spatial structure peculiarities of influenza A virus matrix M1 protein in an acidic solution that simulates the internal lysosomal medium. [J] . Shishkov A, Bogacheva E, Fedorova N, The FEBS journal . 2011,第24期

机译：模拟内部溶酶体介质的酸性溶液中甲型流感病毒基质M1蛋白的空间结构特征。
4. INFLUENZA A VIRUS PARTICLES AS A SUBSTRATE FOR BROMELAIN: REVEALING OF THE MATRIX Ml PROTEIN ACCESSIBILITY FOR LIMITED PROTEOLYSIS [C] . Larisa V. Kordyukova, Marina V. Serebryakova, Yulia A. Smirnova the European Peptide Symposium . 2007

机译：甲型流感病毒颗粒作为菠萝蛋白酶的基材：揭示了有限蛋白水解的基质ML蛋白质可接近性
5. Functional studies of C-terminal domain of influenza A virus matrix 1(M1) protein in virus replication [D] . Xiang, Xiaoxiao 2011

机译：甲型流感病毒基质1（M1）蛋白C末端域在病毒复制中的功能研究
6. The in situ spatial arrangement of the influenza A virus matrix protein M1 assessed by tritium bombardment [O] . Alexander V. Shishkov, Vitalii I. Goldanskii, Ludmila A. Baratova, 1999

机译：用tri轰击评估甲型流感病毒基质蛋白M1的原位空间排列
7. The in situ spatial arrangement of the influenza A virus matrix protein M1 assessed by tritium bombardment [O] . Shishkov, Alexander V., Goldanskii, Vitalii I., Baratova, Ludmila A., 1999

机译：用tri轰击评估甲型流感病毒基质蛋白M1的原位空间排列
8. Crystallized N-terminal domain of influenza virus matrix protein M1 and method of determining and using same [R] . 2000

机译：流感病毒基质蛋白m1的结晶N-末端结构域及其测定和使用方法

The in situ spatial arrangement of the influenza A virus matrix protein M1 assessed by tritium bombardment

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