α-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration

David K. Jin; Jean Vacher; Miriam H. Feuerman

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α-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration

机译：肝再生过程中介导Afr2调节的α-甲胎蛋白基因序列

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α-fetoprotein (AFP) gene expression occurs in the yolk sac, in the fetal liver and gut, and in the adult liver during regeneration and tumorigenesis. Two unlinked genes determine the level of AFP gene expression in adult mice: Afr1 regulates the basal level of expression in the normal adult liver, and Afr2 regulates the increase in expression during liver regeneration. It has been shown that AFP-derived transgenes, including the sequences between -1,010 and -838 bp and between -118 bp and the transcriptional start site were induced appropriately during liver regeneration and were Afr2-regulated.

机译：甲胎蛋白（AFP）基因表达发生在卵黄囊，胎儿肝脏和肠道以及成年肝脏中。两个未链接的基因决定成年小鼠中AFP基因表达的水平：Afr1调节正常成年肝脏中基础表达的水平，而Afr2调节肝脏再生过程中表达的增加。已经显示，在肝再生期间适当地诱导了AFP衍生的转基因，包括-1,010和-838 bp之间以及-118 bp之间的序列和转录起始位点，并且被Afr2调节。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1998年第15期|p.8767-8772|共6页
作者
David K. Jin; Jean Vacher; Miriam H. Feuerman;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. SEQUENCE REQUIREMENTS FOR AFR-2 REGULATION OF ALPHA-FETOPROTEIN GENE EXPRESSION DURING LIVER REGENERATION [J] . Jin DK, Feuerman MH Somatic Cell and Molecular Genetics . 1996,第3期

机译：肝再生过程中α-胎蛋白基因表达的AFR-2调控序列要求
2. Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome [J] . Rajeswari Banerji, Robert V. Skibbens, M. Kathryn Iovine Biology Open . 2017,第12期

机译：Cohesin介导罗伯茨综合征斑马鱼再生鳍模型中Esco2依赖性转录调控Cohesin介导罗伯茨综合征斑马鱼再生鳍模型中Esco2依赖性转录调控Cohesin介导Roberts综合征斑马鱼再生鳍模型中Esco2依赖性转录调控。
3. Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome Cohesin mediates Esco2-dependent transcriptional regulation in a zebrafish regenerating fin model of Roberts Syndrome [J] . Rajeswari Banerji, Robert V. Skibbens, M. Kathryn Iovine Biology Open . 2017,第12期

机译：Cohesin介导罗伯茨综合征斑马鱼再生鳍模型中Esco2依赖性转录调控Cohesin介导罗伯茨综合征斑马鱼再生鳍模型中Esco2依赖性转录调控Cohesin介导Roberts综合征斑马鱼再生鳍模型中Esco2依赖性转录调控。
4. Substrate-Mediated Nanoparticle/Gene Delivery to MSC Spheroids and the Applications in Peripheral Nerve Regeneration [C] . Ting-Chen Tseng, Shan-hui Hsu 26th European conference on biomaterials 2014 . 2014

机译：基质介导的纳米颗粒/基因向MSC球体的传递及其在周围神经再生中的应用
5. The role of Notch signaling in oval cell-mediated liver regeneration . [D] . Darwiche, Houda. 2009

机译：Notch信号在卵圆细胞介导的肝再生中的作用。
6. α-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration [O] . David K. Jin, Jean Vacher, Miriam H. Feuerman 1998

机译：肝再生过程中介导Afr2调节的α-甲胎蛋白基因序列
7. -Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration [O] . D. K. Jin, J. Vacher, M. H. Feuerman 1998

机译：- 在肝再生过程中介导AFR2调节的临床基因序列
8. Value of the Indirect Immunoradiometric Assay of Serum alpha - Fetoprotein in Detecting Liver Regeneration and Neoplastic Transformation in Chronic Liver Disease. Part of a Coordinated Programme on in Vitro Assay Techniques. Final [R] . Voiculetz, N. 1979

机译：血清甲胎蛋白间接免疫放射分析法检测慢性肝病肝再生和肿瘤转化的价值。体外分析技术协调计划的一部分。最后

α-Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration

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