T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice

RuiRong Yuan; Arturo Casadevall; Jin Oh

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T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice

机译：T细胞与被动抗体协同改变小鼠新隐球菌感染

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Cryptococcus neoformans is an encapsulated fungus that is a major cause of meningitis in patients with AIDS. In immunocompetent mice, administration of IgG1 mAb protects against cryptococcal infection, whereas admini- stration of IgG3 is not protective and can accelerate the infection. In beige mice with impaired natural killer cell function, the effects of IgG1 and IgG3 are similar to those observed in immunocompetent mice, suggesting that natural killer cells are not crucial for antibody-mediated modulation of cryptococcal infection.

机译：新型隐球菌是一种封装的真菌，是艾滋病患者脑膜炎的主要原因。在具有免疫能力的小鼠中，给予IgG1 mAb可以预防隐球菌感染，而给予IgG3则不能起到保护作用，可以加速感染。在具有自然杀伤细胞功能受损的米色小鼠中，IgG1和IgG3的作用与在免疫能力强的小鼠中观察到的相似，这表明自然杀伤细胞对于抗体介导的隐球菌感染的调控并非至关重要。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第6期|p.2483-2488|共6页
作者
RuiRong Yuan; Arturo Casadevall; Jin Oh;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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专利

1. T CELLS COOPERATE WITH PASSIVE ANTIBODY TO MODIFY CRYPTOCOCCUS NEOFORMANS INFECTION IN MICE [J] . Yuan RR., Oh J., Scharff MD., Proceedings of the National Academy of Sciences of the United States of America . 1997,第6期

机译：T细胞与被动抗体协同修饰小鼠新球菌新城疫感染
2. Monoclonal antibodies to Cryptococcus neoformans capsular polysaccharide modify the course of intravenous infection in mice. [J] . S Mukherjee, S Lee, J Mukherjee, Infection and immunity . 1994,第3期

机译：新型隐球菌荚膜多糖的单克隆抗体可改变小鼠静脉感染的过程。
3. Antibodies Produced in Response to Cryptococcus neoformans Pulmonary Infection in Mice Have Characteristics of Nonprotective Antibodies [J] . Oscar Zaragoza, Arturo Casadevall Infection and immunity . 2004,第7期

机译：对小鼠新隐球菌肺部感染产生反应的抗体具有非保护性抗体的特征
4. Identifying pulmonary Cryptococcus neoformans infection by serum surface-enhanced Raman spectroscopy [C] . Hao Lin, He Zhang, Jiaming Chen, International Conference on Optics in Health Care and Biomedical Optics;Chinese Optical Society;Society of Photo-Optical Instrumentation Engineers;Tsinghua University . 2019

机译：通过血清表面增强拉曼光谱鉴定肺新隐球菌感染
5. Complement, passively administered antibodies, and disease dissemination in mice infected with Cryptococcus neoformans or Cryptococcus gattii [D] . Mershon, Kileen Louise 2008

机译：补体，被动施用的抗体以及在新型隐球菌或gryptococcus gattii感染的小鼠中的疾病传播
6. T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice [O] . RuiRong Yuan, Arturo Casadevall, Jin Oh, 1997

机译：T细胞与被动抗体协同作用以修饰小鼠新隐球菌感染
7. Passive Immunization with Melanin-Binding Monoclonal Antibodies Prolongs Survival of Mice with Lethal Cryptococcus neoformans Infection [O] . Rosas, Ángel L., Nosanchuk, Joshua D., Casadevall, Arturo 2001

机译：黑色素结合单克隆抗体的被动免疫延长了致命的新型隐球菌感染小鼠的存活。

T cells cooperate with passive antibody to modify Cryptococcus neoformans infection in mice

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