Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein

Benjamin H. Lee; Michael B. Mathews

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein

【24h】

Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein

机译：转录共激活因子cAMP反应元件结合蛋白介导腺病毒E1A癌蛋白诱导人增殖细胞核抗原启动子

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The proliferating cell nuclear antigen (PCNA), a crucial component of eukaryotic cell cycle and DNA replication complexes, is induced by the adenovirus E1A 243R oncoprotein through a cis-acting element termed the PERE (PCNA-E1A responsive element). The PERE contains a se- quence homologous to an activating transcription factor (ATF) motif, and ATF-1 is a major component of PERE- protein complexes. We have identified a second PERE-binding protein, the cAMP response element binding protein (CREB) transcription factor, which forms heterodimers with ATF-1 at this site.

机译：腺病毒E1A 243R癌蛋白通过称为PERE的顺式作用元件（PCNA-E1A响应元件）诱导了增殖细胞核抗原（PCNA），它是真核细胞周期和DNA复制复合物的重要组成部分。 PERE包含与激活转录因子（ATF）基序同源的序列，而ATF-1是PERE蛋白复合物的主要成分。我们已经鉴定出第二个PERE结合蛋白，即cAMP反应元件结合蛋白（CREB）转录因子，它在该位点与ATF-1形成异二聚体。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第9期|p.4481-4486|共6页
作者
Benjamin H. Lee; Michael B. Mathews;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. A complex promoter element mediates transactivation of the human proliferating cell nuclear antigen promoter by the 243-residue adenovirus E1A oncoprotein. [J] . C Labrie, G F Morris, M B Mathews Molecular and Cellular Biology . 1993,第3期

机译：复杂的启动子元件通过243个残基的腺病毒E1A癌蛋白介导人类增殖细胞核抗原启动子的反式激活。
2. Modulation of transcriptional activation of the proliferating cell nuclear antigen promoter by the adenovirus E1A 243-residue oncoprotein depends on proximal activators. [J] . G F Morris, C Labrie, M B Mathews Molecular and Cellular Biology . 1994,第1期

机译：腺病毒E1A 243-残基癌蛋白对增殖细胞核抗原启动子转录激活的调控取决于近端激活剂。
3. TRANSCRIPTION FACTORS RFX1/EF-C AND ATF-1 ASSOCIATE WITH THE ADENOVIRUS E1A-RESPONSIVE ELEMENT OF THE HUMAN PROLIFERATING CELL NUCLEAR ANTIGEN PROMOTER [J] . Labrie C, Lee BH, Mathews MB Nucleic Acids Research . 1995,第18期

机译：转录因子RFX1 / EF-C和ATF-1与人类增殖细胞核抗原启动子的腺病毒E1A响应元件相关
4. INDUCTION OF ANTIGEN-SPECIFIC IMMUNE RESPONSES BASED ON CHEMICAL MODIFICATION OF ANTIGEN PROTEINS TARGETING TO ANTIGEN PRESENTATING CELLS [C] . Yasuomi Yamasaki, Tomoko Ikenaga, Yoshinobu Takakura Proceedings of the 29th Annual Meeting of the Controlled Release Society . 2002

机译：基于针对抗原预增敏细胞的抗原蛋白的化学修饰，诱导抗原特异性免疫反应
5. The effect of iron-containing particulates on induction and activity of the transcription factors nuclear factor κB, early growth response 1, and activating transcription factor 3 in human lung epithelial cells [D] . Buelow, Laura Cecile 2007

机译：含铁颗粒物对人肺上皮细胞转录因子核因子κB的诱导和活性，早期生长反应1和活化转录因子3的影响
6. Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein [O] . Benjamin H. Lee, Michael B. Mathews 1997

机译：转录共激活因子cAMP反应元件结合蛋白介导腺病毒E1A癌蛋白诱导人增殖细胞核抗原启动子
7. A complex promoter element mediates transactivation of the human proliferating cell nuclear antigen promoter by the 243-residue adenovirus E1A oncoprotein. [O] . Labrie, C, Morris, G F, Mathews, M B 1993

机译：复杂的启动子元件通过243个残基的腺病毒E1A癌蛋白介导人类增殖细胞核抗原启动子的反式激活。
8. In vitro Antigen-Specific Antibody Response to the Species-Specific Surface Protein Antigens of Typhus Group Rickettsiae by Human Peripheral Blood Mononuclear Cells. Generation of an Antigen-Dependent Suppressor T Cell [R] . Misiti, J., Dasch, G. A. 1985

机译：体外抗原特异性抗体对人外周血单个核细胞对斑疹伤寒组立克次体的物种特异性表面蛋白抗原的反应。产生抗原依赖性抑制T细胞

Transcriptional coactivator cAMP response element binding protein mediates induction of the human proliferating cell nuclear antigen promoter by the adenovirus E1A oncoprotein

摘要

著录项

相似文献

相关主题

期刊订阅