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Rappaport rules: Cleavage furrow induction in animal cells

机译:Rappaport规则:在动物细胞中诱导开沟

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Unfortuately, none of these cytological observations would conclusively distinguish whether the Rappaport furrow was generated by White/Borisy focusing secondary to normal furrow assembly elsewhere versus the older models in which signals emanating from the asters directly affect the cortex. The best way of distinguishing these models might be to artificially generate tension gradients in anaphase cells with no asters and ask if they self-focus into bona fide furrows.
机译:不幸的是,这些细胞学观察都无法最终区分拉帕波特犁沟是否是由其他地方正常犁沟组装之后的白/鲍里斯集中产生的,而不是由紫发出的信号直接影响皮层的较旧模型。区分这些模型的最好方法可能是在没有星号的后期细胞中人工生成张力梯度,并询问它们是否自动聚焦到真正的犁沟中。

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