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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Reexamination of human T cell lymphotropic virus (HTLV-I/II) prevalence
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Reexamination of human T cell lymphotropic virus (HTLV-I/II) prevalence

机译:复查人类T细胞淋巴病毒(HTLV-I / II)患病率

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摘要

In the United States, blood donors are being screened for infection with human T cell lymphotropic viruses I and II (HTLV-I/II) by serologic means, which detect anti- bodies to the structural proteins of these viruses. Because patients with mycosis fungoides (MF) usually do not have such antibodies even though their cells harbor HTLV-I Tax and/or pol proviral sequences, it was questioned whether the preva- lence of HTLV infection among healthy blood donors may also be underestimated by current means of testing.
机译:在美国,正在通过血清学方法筛查献血者是否感染了人类T细胞淋巴病毒I和II(HTLV-I / II),该方法可检测这些病毒的结构蛋白抗体。由于蕈样真菌病(MF)患者即使其细胞带有HTLV-I Tax和/或pol前病毒序列,通常也没有这种抗体,因此有人质疑健康献血者中HTLV感染的发生率是否也可能被低估了吗?当前的测试手段。

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