The catalytic domain of λ site-specific recombinase

Radhakrishna S. Tirumalai; Erica Healey; Arthur Landy

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >The catalytic domain of λ site-specific recombinase

【24h】

The catalytic domain of λ site-specific recombinase

机译：λ位点特异性重组酶的催化结构域

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The Escherichia coli phage λ integrase pro- tein (Int) belongs to the large Int family of site-specific recombinases. It is a heterobivalent DNA binding protein that makes use of a high energy covalent phosphotyrosine inter- mediate to catalyze integrative and excisive recombination at specific chromosomal sites (att sites). A 293-amino acid car- boxy-terminal fragment of Int (C65) has been cloned, char- acterized, and used to further dissect the protein.

机译：大肠杆菌噬菌体λ整合酶蛋白（Int）属于位点特异性重组酶的大型Int家族。它是一种异双价DNA结合蛋白，利用高能共价磷酸酪氨酸介导在特定染色体位点（att位点）上的整合和激进重组。 Int（C65）的293个氨基酸的羧基末端片段已被克隆，鉴定并用于进一步分解该蛋白。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第12期|p.6104-6109|共6页
作者
Radhakrishna S. Tirumalai; Erica Healey; Arthur Landy;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Functional analysis of the C-terminal domains of the site-specific recombinases XerC and XerD. [J] . Ferreira H, Butler Cole B, Burgin A, Journal of Molecular Biology . 2003,第1期

机译：位点特异性重组酶XerC和XerD的C端结构域的功能分析。
2. Trans Cooperativity by a Split DNA Recombinase: The Central and Catalytic Domains of Bacteriophage Lambda Integrase Cooperate in Cleaving DNA Substrates When the Two Domains Are not Covalently Linked. [J] . Subramaniam S, Kamadurai HB, Foster MP Journal of Molecular Biology . 2007,第2期

机译：通过拆分的DNA重组酶的反式协同性：当两个域未共价连接时，噬菌体λ整合酶的中央域和催化域在切割DNA底物中协同工作。
3. Single molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombination [J] . Fan Hsiu-Fang, Cheng Yong-Song, Ma Chien-Hui, Nucleic Acids Research . 2015,第6期

机译：Cre和Flp位点特异性重组酶的催化五单元突变体的单分子TPM分析：五单元残基对重组的化学前步骤的贡献
4. Imaging site-specific peptide-targeting in tumor tissues using spectral- domain optical coherence tomography [C] . Lixin Ma, Miao Zhang, Ping Yu Advanced biomedical and clinical diagnostic systems IX . 2011

机译：使用光谱域光学相干断层扫描成像在肿瘤组织中靶向位点的多肽
5. Structural and biochemical studies of site-specific recombinases. [D] . Yuan, Peng. 2008

机译：位点特异性重组酶的结构和生化研究。
6. The catalytic domain of λ site-specific recombinase [O] . Radhakrishna S. Tirumalai, Erica Healey, Arthur Landy 1997

机译：λ位点特异性重组酶的催化结构域
7. Trans Cooperativity by a Split DNA Recombinase: The Central and Catalytic Domains of Bacteriophage Lambda Integrase Cooperate in Cleaving DNA Substrates When the Two Domains Are not Covalently Linked [O] . Srisunder Subramaniam, Hari B. Kamadurai, Mark P. Foster 2007

机译：通过分裂DNA重组酶进行反式协作：当两个域不共价连接时，噬菌体λλ整合酶的中央和催化结构域在切割DNA底物中配合
8. Site-Specific Serine Recombinases and Methods of Their Use. [R] . Padidam, M. 2005

机译：位点特异性丝氨酸重组酶及其使用方法。

The catalytic domain of λ site-specific recombinase

摘要

著录项

相似文献

相关主题

期刊订阅