DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis

Ginger E. Carney; Andrew A. Wade; Rajat Sapra

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis

【24h】

DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis

机译：DHR3是蜕皮激素诱导的编码果蝇核受体的早晚基因，是胚胎发生所必需的

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Response to the steroid hormone ecdysone in Drosophila is controlled by genetic regulatory hierarchies that include eight members of the nuclear receptor protein family. The DHR3 gene, located within the 46F early-late ecdysone- inducible chromosome puff, encodes an orphan nuclear re- ceptor that recently has been shown to exert both positive and negative regulatory effects in the ecdysone-induced genetic hierarchies at metamorphosis. We used a reverse genetics approach to identify 11 DHR3 mutants from a pool of lethal mutations in the 46F region on the second chromosome. Two DHR3 mutations result in amino acid substitutions within the conserved DNA binding domain.

机译：果蝇中对类固醇激素蜕皮激素的反应受包括八种核受体蛋白家族成员的遗传调控体系的控制。 DHR3基因位于46F早期蜕皮激素诱导的染色体粉扑内，编码一个孤儿核受体，最近已证明它在蜕皮激素诱导的蜕皮激素遗传结构中具有正负调节作用。我们使用反向遗传学方法从第二条染色体上46F区的致死突变库中识别出11个DHR3突变体。两个DHR3突变导致保守的DNA结合域内发生氨基酸置换。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1997年第22期|p.12024-12029|共6页
作者
Ginger E. Carney; Andrew A. Wade; Rajat Sapra;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. Expression of the early-late gene encoding the nuclear receptor HR3 suggests its involvement in regulating the vitellogenic response to ecdysone in the adult mosquito. [J] . Kapitskaya MZ, Li C, Miura K, Molecular and Cellular Endocrinology . 2000,第1a2期

机译：编码核受体HR3的早期晚期基因的表达表明其参与调节成年蚊子对蜕皮激素的卵黄反应。
2. The Drosophila fragile X protein dFMR1 is required during early embryogenesis for pole cell formation and rapid nuclear division cycles [J] . Deshpande G, Calhoun G, Schedl P Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2006,第3期

机译：果蝇脆弱的X蛋白dFMR1在胚胎早期发育中需要极细胞形成和快速的核分裂周期
3. The Drosophila Fragile X Protein dFMR1 Is Required During Early Embryogenesis for Pole Cell Formation and Rapid Nuclear Division Cycles [J] . Girish Deshpande, Gretchen Calhoun, Paul Schedl Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2006,第3期

机译：果蝇易碎X蛋白dFMR1是早期胚胎发生中极细胞形成和快速核分裂周期所必需的。
4. HMIML: Hierarchical Multi-Instance Multi-Label Learning of Drosophila Embryogenesis Images Using Convolutional Neural Networks [C] . Tiange Li, Yang Yang, Hong-Bin Shen IEEE International Conference on Bioinformatics and Biomedicine . 2018

机译：HMIML：使用卷积神经网络的果蝇胚胎发生图像的分层多实例多标签学习
5. RSF1 and RSF2, nuclear genes encoding proteins required for respiratory growth and mitochondrial DNA maintenance in Saccharomyces cerevisiae. [D] . Lu, Lin. 2003

机译：RSF1和RSF2是编码酿酒酵母中呼吸生长和线粒体DNA维持所需的蛋白质的核基因。
6. DHR3 an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor is required for embryogenesis [O] . Ginger E. Carney, Andrew A. Wade, Rajat Sapra, 1997

机译：DHR3是蜕皮激素诱导的编码果蝇核受体的早晚基因是胚胎发生所必需的
7. The E75 ecdysone-inducible gene responsible for the 75B early puff in Drosophila encodes two new members of the steroid receptor superfamily. [O] . W A Segraves, D S Hogness 1990

机译：在果蝇早期粉扑中负责的E75蜕皮诱导型基因编码了两种新成员的类固醇受体超家族。

DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis

摘要

著录项

相似文献

相关主题

期刊订阅