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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Phosphotyrosine signaling and the single cell: metazoan boundary
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Phosphotyrosine signaling and the single cell: metazoan boundary

机译:磷酸酪氨酸信号与单细胞:后生界

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摘要

In considering precursors to multicellular organisms it is widely supposed that the chlorophyta (chlorophlast containing single-celled organisms) are the precursors to plants (33). Bec- ause of the recognition of the close amino acid sequence similarities that link fungi and animals (17,18), a common, single-celled precursor to fungi and animals might be enter- tained. However, any precursor to animals might logically be expected to engage in phosphotyrosine signaling. Finding a phosphotyrosine signaling molecule in an organism capable of growing as a single cell and also of multicellular development greatly heightens the evolutionary interest of the discovery of Williams and coworkers (2).
机译:在考虑多细胞生物的前体时,普遍认为叶绿素(含有叶绿体的单细胞生物)是植物的前体(33)。由于认识到了连接真菌和动物的紧密的氨基酸序列相似性(17,18),因此可以考虑是真菌和动物的常见单细胞前体。但是,从逻辑上讲,任何动物的前体都可能参与磷酸酪氨酸信号转导。在能够作为单细胞生长并且也具有多细胞发育能力的生物体中发现磷酸酪氨酸信号分子,极大地提高了威廉姆斯及其同事发现的进化兴趣(2)。

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