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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition
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Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition

机译:GMP-17的表征,一种颗粒膜蛋白,在靶细胞识别后可移动至自然杀伤细胞的质膜

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摘要

Cytotoxic lymphocytes are characterized by their inclusion of cytoplasmic granules that fuse with the plasma membrane following target cell recognition. We pre- viously identified a cytotoxic granule membrane protein des- ignated p15-TIA-1 that is immunochemically related to an RNA-recognition motif (RRM)-type RNA-binding protein des- ignated p40-TIA-1.
机译:细胞毒性淋巴细胞的特征在于它们包含在靶细胞识别后与质膜融合的细胞质颗粒。我们以前鉴定了一种细胞毒性颗粒膜蛋白,称为p15-TIA-1,该蛋白与RNA识别基序(RRM)型RNA结合蛋白,称为p40-TIA-1,在免疫化学上相关。

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