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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Short-term synaptic enhancement and long-term potentiation in neocortex
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Short-term synaptic enhancement and long-term potentiation in neocortex

机译:新皮层的短期突触增强和长期增强

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摘要

Repetitive stimuli reliably induce long-term potentiation (LTP) of synapses in the upper layers of the granular somatosensory cortex but not the agranular motor cortex of rats. Herein we examine, in these same cortical areas, short-term changes in synaptic strength that occur during the LTP induction period. θ-Burst stimulation produced a strong short-term enhancement of synapses in the granular area but only weak enhancement in the agranular area. The magnitude of enhancement during stimulation was strongly correlated with the magnitude of LTP subsequently expressed.
机译:重复刺激可靠地诱导大鼠体感皮层的上层而不是粒状运动皮层上突触的长期增强(LTP)。本文中,我们研究了在这些相同的皮质区域中LTP诱导期发生的突触强度的短期变化。 θ-Burst刺激在颗粒区域产生短期强烈的突触增强,而在颗粒区域仅产生较弱的增强。刺激过程中增强的强度与随后表达的LTP强度密切相关。

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