~31P magnetic resonance spectroscopy of the Sherpa heart: A phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia

P. W. Hochachka; C. M. Clark; J. E. Holden

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~31P magnetic resonance spectroscopy of the Sherpa heart: A phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia

机译：夏尔巴人心脏的〜31P磁共振波谱：抗低压缺氧的代谢防御的磷酸肌酸/腺苷三磷酸信号

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Of all humans thus far studied, Sherpas are considered by many high-altitude biomedical scientists as most exquisitely adapted for life under continuous hypobaric hypoxia. However, little is known about how the heart is protected in hypoxia. Hypoxia defense mechanisms in the Sherpa heart were explored by in vivo, noninvasive ~31P mag- netic resonance spectroscopy.

机译：在迄今研究的所有人类中，许多高海拔生物医学科学家都认为夏尔巴协作最适合连续低压缺氧生活。但是，对缺氧如何保护心脏知之甚少。夏尔巴人心脏的缺氧防御机制已通过体内无创〜31P磁共振波谱法进行了探索。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第3期|p.1215-1220|共6页
作者
P. W. Hochachka; C. M. Clark; J. E. Holden;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Measurement of Phosphocreatine to Adenosine Triphosphate Ratio in Normal Human Heart by 31P Magnetic Resonance Spectroscopy [J] . B. Rajagopalan, G.K. Radda, M.J. Biackledge, Clinical Science . 1986,第s15期

机译：31P磁共振波谱法测定正常人心脏中磷酸肌酸与三磷酸腺苷的比值
2. Evidence for a "metabolically inactive" inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T [J] . Tiret Brice, Brouillet Emmanuel, Valette Julien Journal of Cerebral Blood Flow and Metabolism: Official Journal of the International Society of Cerebral Blood Flow and Metabolism . 2016,第9期

机译：使用局部31P饱和转移磁共振波谱在11.7 T时大鼠脑中腺苷三磷酸合酶反应中“代谢失活”的无机磷酸盐库的证据
3. 31P nuclear magnetic resonance study of steady-state adenosine 5′-triphosphate levels during graded hypoxia in the isolated perfused rat kidney [J] . G. K. Radda, J. D. Tange, J. G. G. Ledingham, Clinical Science . 1988,第4期

机译：31P核磁共振研究分级灌注缺氧大鼠离体肾脏中稳态5'-三磷酸腺苷水平
4. Metabolomics of Hypobaric Hypoxia: Oxidative Stress and its Metabolic Signature [C] . Denise U. Sonntag, Jacqueline Pichler Hefti, Urs Hefti, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2010

机译：缺氧的代谢组学：氧化应激及其代谢签名
5. Mechanisms and pathways of inositol phosphate degradation: Evidence from phosphate oxygen stable isotope ratios and 31P nuclear magnetic resonance spectroscopy [D] . Wu, Jiangqi. 2014

机译：磷酸肌醇磷酸盐降解的机制和途径：来自磷酸盐稳定同位素比和31P核磁共振光谱的证据
6. 31P magnetic resonance spectroscopy of the Sherpa heart: a phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia. [O] . P W Hochachka, C M Clark, J E Holden, 1996

机译：夏尔巴人心脏的31P磁共振波谱：抗低压缺氧的代谢防御的磷酸肌酸/腺苷三磷酸信号。
7. 31P magnetic resonance spectroscopy of the Sherpa heart: a phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia. [O] . Hochachka, P W, Clark, C M, Holden, J E, 1996

机译：夏尔巴人心脏的31P磁共振波谱：抗低压缺氧的代谢防御的磷酸肌酸/腺苷三磷酸信号。

~31P magnetic resonance spectroscopy of the Sherpa heart: A phosphocreatine/adenosine triphosphate signature of metabolic defense against hypobaric hypoxia

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