Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer

Corina J. A. Moen; Peter C. Groot; Augustinus A. M. Hart

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Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer

机译：小鼠中结肠癌易感性（Scc）基因的精细定位，与已知在结肠癌中发生体细胞突变的基因不同

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The predisposition to colon cancer is multi- genetically controlled in animals and probably also in hu- mans. We have analyzed the multigenic control of suscepti- bility to 1,2-dimethylhydrazine-induced colon tumors in mice by using a set of 20 homozygous CcS/Dem recombinant congenic strains, each of which contains a different random subset of =12.5/100 of genes from the susceptible strain STS/A and 87.5/100 of genes from the relatively resistant strain BALB/cHeA.

机译：结肠癌的易感性在动物乃至人类中受到多基因控制。我们通过使用一组20个纯合的CcS / Dem重组同基因菌株，分析了小鼠对1,2-二甲基肼诱发的结肠肿瘤敏感性的多基因控制，每个菌株均包含= 12.5 / 100的不同随机子集。来自易感菌株STS / A的基因和相对抗性菌株BALB / cHeA的基因的87.5 / 100。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第3期|p.1082-1086|共5页
作者
Corina J. A. Moen; Peter C. Groot; Augustinus A. M. Hart;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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2. Mapping Six New Susceptibility to Colon Cancer (Scc) Loci Using a Mouse Interspecific Backcross [J] . Chevonne D. Eversley, David W. Threadgill, R. Scott Pearsall, G3: Genes, Genomes, Genetics . 2012,第12期

机译：映射六个新的易感性使用小鼠种间回交结肠癌（Scc）基因座。
3. Intrinsic resistance to apoptosis of colon epithelial cells is a potential determining factor in the susceptibility of the A/J mouse strain to dimethylhydrazine-induced colon tumorigenesis. [J] . Oumouna-Benachour K, Oumouna M, Zerfaoui M, Molecular Carcinogenesis . 2007,第12期

机译：对结肠上皮细胞凋亡的内在抗性是A / J小鼠品系对二甲基肼诱导的结肠肿瘤发生的敏感性的潜在决定因素。
4. Fluorescence colon tumor imaging by i.v. administered indocyanine green in a rat model of colon carcinogenesis [C] . Nobuhiko Onda, Reiko Mizutani-Morita, Susumu Yamashita, International Photodynamic Association World Congress;Society of Photo-Optical Instrumentation Engineers;International Photodynamic Association . 2019

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5. Linking Inflammation To Tumorigenesis In A Mouse Model of High Fat Diet-Enhanced Colon Cancer: Does Fat Type Matter? [D] . Day, Stani Dellyn. 2012

机译：在高脂饮食增强结肠癌的小鼠模型中将炎症与肿瘤发生联系起来：脂肪类型重要吗？
6. Fine mapping of colon tumor susceptibility (Scc) genes in the mouse different from the genes known to be somatically mutated in colon cancer. [O] . C J Moen, P C Groot, A A Hart, 1996

机译：小鼠中结肠肿瘤易感性（Scc）基因的精细定位与已知在结肠癌中发生体细胞突变的基因不同。
7. Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer. [O] . Moen, C J, Groot, P C, Hart, A A, 1996

机译：小鼠中结肠肿瘤易感性（Scc）基因的精细定位，与已知在结肠癌中发生体细胞突变的基因不同。

Fine mapping of colon tumor susceptibility (Scc) genes in the mouse, different from the genes known to be somatically mutated in colon cancer

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