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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Equine rhinovirus 1 is more closely related to foot-and-mouth disease virus than to other picornaviruses
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Equine rhinovirus 1 is more closely related to foot-and-mouth disease virus than to other picornaviruses

机译:马鼻病毒1与口蹄疫病毒的关系比与其他小核糖核酸病毒的关系更紧密

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摘要

Equine rhinovirus 1 (ERhV1) is a respira tory pathogen of horses which has an uncertain taxonomic status. We have determined the nucleotide sequence of the ERhV1 genome except for a small region at the 5' end. The predicted polyprotein was encoded by 6741 nucleotides and possessed a typical picornavirus proteolytic cleavage pattern, including a leader polypeptide. The genomic structure and predicted amino acid sequence of ERhV1 were more similar to those of foot-and-mouth disease viruses (FMDVs), the only members of the aphthovirus genus, than to those of other picornaviruses.
机译:马鼻病毒1(ERhV1)是马的呼吸道病原体,具有不确定的分类学地位。我们已经确定了ERhV1基因组的核苷酸序列,除了5'端的一个小区域。预测的多蛋白由6741个核苷酸编码,并具有典型的小核糖核酸病毒蛋白水解切割模式,包括前导多肽。 ERhV1的基因组结构和预测的氨基酸序列与口蹄疫病毒(FMDVs)(仅是水痘病毒属的唯一成员)的基因组结构和预测的氨基酸序列相比,与其他小核糖核酸病毒的相似。

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