Recognition of diverse sequences by class I zinc fingers: Asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich sequence elements

Joseph A. Gogos; Jingmin Jin; Hong Wan

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Recognition of diverse sequences by class I zinc fingers: Asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich sequence elements

机译：通过I类锌指识别各种序列：CF2II与富含A + T的序列元素之间相互作用的不对称性和对特异性的间接影响

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The Drosophila CF2II protein, which con- tains zinc fingers of the Cys_2His_2 type and recognizes an A+T-rich sequence, behaves in cell culture as an activator of a reporter chloramphenicol acetyltransferase gene. This ac- tivity depends on C-terminal but not N-terminal zinc fingers, as does in vitro DNA binding. By site-specific mutagenesis and binding site selection, we define the critical amino acid-base interactions.

机译：果蝇CF2II蛋白包含Cys_2His_2类型的锌指并识别富含A + T的序列，在细胞培养中表现为报告氯霉素乙酰转移酶基因的激活剂。这种活性取决于C末端而不是N末端的锌指，体外DNA结合也是如此。通过位点特异性诱变和结合位点选择，我们定义了关键的氨基酸-碱基相互作用。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第5期|p.2159-2164|共6页
作者
Joseph A. Gogos; Jingmin Jin; Hong Wan;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso [J] . Bethany A. Buck-Koehntop, Robyn L. Stanfield, Damian C. Ekiert, Proceedings of the National Academy of Sciences of the United States of America . 2012,第38期

机译：锌指蛋白Kaiso识别甲基化和特定DNA序列的分子基础
2. A large protein containing zinc finger domains binds to related sequence elements in the enhancers of the class I major histocompatibility complex and kappa immunoglobulin genes. [J] . A S Baldwin, K P LeClair, H Singh, Molecular and Cellular Biology . 1990,第4期

机译：含有锌指结构域的大蛋白与I类主要组织相容性复合体和Kappa免疫球蛋白基因的增强子中的相关序列元件结合。
3. The Human CCHC-type Zinc Finger Nucleic Acid-Binding Protein Binds G-Rich Elements in Target mRNA Coding Sequences and Promotes Translation [J] . Daniel Benhalevy, Sanjay K. Gupta, Charles H. Danan, Cell Reports . 2017,第12期

机译：人CCHC型锌指核酸结合蛋白在靶mRNA编码序列中结合富含G的元素并促进翻译
4. Algorithm for Real-Time Finger Spelling Alphabet Recognition in Video Sequences [C] . Filip Csoka, Jaroslav Polec Signal Processing Symposium . 2017

机译：实时手指拼写字母识别视频序列中的算法
5. Determination of the Consensus Target Sequences Recognized by ZNFO, A Novel Oocyte-specific Zinc Finger Transcription Factor in Cattle [D] . Zhang, Mingxiang 2018

机译：牛卵母细胞特异性锌指转录因子ZNFO识别的共有靶序列的确定
6. Recognition of diverse sequences by class I zinc fingers: asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich elements. [O] . J A Gogos, J Jin, H Wan, 1996

机译：通过I类锌指识别各种序列：CF2II与富含A + T的元素之间相互作用中的不对称性和对特异性的间接影响。
7. Recognition of diverse sequences by class I zinc fingers: asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich elements. [O] . Gogos, J A, Jin, J, Wan, H, 1996

机译：通过I类锌指识别各种序列：CF2II与富含A + T的元素之间相互作用中的不对称性和对特异性的间接影响。

Recognition of diverse sequences by class I zinc fingers: Asymmetries and indirect effects on specificity in the interaction between CF2II and A+T-rich sequence elements

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