Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes

Oleg V. Kovalenko; Annemieke W. Plug; Thomas Haaf

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Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes

机译：哺乳动物泛素结合酶Ubc9与Rad51重组蛋白相互作用，并位于突触复合物中

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Hsubc9, a human gene encoding a ubiquitin- conjugating enzyme, has been cloned. The 18-kDa HsUbc9 protein is homologous to the ubiquitin-conjugating enzymes Hus5 of Schizosaccharomyces pombe and Ubc9 of Saccharomyces cerevisiae. The Hsubc9 gene complements a ubc9 mutation of S. cerevisiae. It has been mapped to chromosome 16p13.3 and is expressed in many human tissues, with the highest levels in testis and thymus. According to the Gal4 two-hybrid system analysis, HsUbc9 protein interacts with human recombination protein Rad51.

机译：已经克隆了编码泛素结合酶的人类基因Hsubc9。 18 kDa HsUbc9蛋白与粟酒裂殖酵母的泛素结合酶Hus5和酿酒酵母Ubc9同源。 Hsubc9基因与酿酒酵母的ubc9突变互补。它已被映射到16p13.3号染色体，并在许多人体组织中表达，在睾丸和胸腺中含量最高。根据Gal4双杂交系统分析，HsUbc9蛋白与人重组蛋白Rad51相互作用。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.2958-2963|共6页
作者
Oleg V. Kovalenko; Annemieke W. Plug; Thomas Haaf;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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1. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes. [J] . Haaf T, Golub EI, Reddy G, Proceedings of the National Academy of Sciences of the United States of America . 1995,第6期

机译：DNA损伤后体细胞中哺乳动物Rad51重组蛋白的核灶及其在突触复合物中的定位。
2. Arabidopsis RAD51, RAD51C and XRCC3 proteins form a complex and facilitate RAD51 localization on chromosomes for meiotic recombination [J] . Hang Su, Zhihao Cheng, Jiyue Huang, PLoS Genetics . 2017,第5期

机译：拟南芥RAD51，RAD51C和XRCC3蛋白形成复合物并促进RAD51在染色体上进行减数分裂重组
3. Synaptonemal Complex Central Region Proteins Promote Localization of Pro-crossover Factors to Recombination Events During Caenorhabditis elegans Meiosis [J] . Cahoon Con K., Helm Jacquellyn M., Libuda Diana E. Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2019,第2期

机译：Synaptonemal Complex Central Region蛋白质促进了在Caenorhabditis elegans Meiosis期间对重组事件的单交叉因子的本地化
4. Characterization of Intact Complexes of Anticancer Drugs and Serum Proteins, Enzymes and Antibodies Using Electrospray Mass Spectrometry [C] . Sool Yeon Cho, James F. Holland, John Roboz ASMS Conference on Mass Spectrometry and Allied Topics . 2008

机译：用电喷雾质谱法表征抗癌药物和血清蛋白，酶和抗体的完整复合物
5. Characterization of mammalian Rad51 in homologous recombination and DNA repair [D] . Malysewich, Michael J. 2009

机译：哺乳动物Rad51同源重组和DNA修复的表征
6. Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. [O] . O V Kovalenko, A W Plug, T Haaf, 1996

机译：哺乳动物泛素结合酶Ubc9与Rad51重组蛋白相互作用并位于突触复合物中。
7. Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes. [O] . Kovalenko, O V, Plug, A W, Haaf, T, 1996

机译：哺乳动物泛素结合酶Ubc9与Rad51重组蛋白相互作用，并位于突触复合物中。

Mammalian ubiquitin-conjugating enzyme Ubc9 interacts with Rad51 recombination protein and localizes in synaptonemal complexes

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