Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver

Tobias R. Kollmann; Massimo Pettoello-Mantovani; Nikos F. Katopodis

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Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver

机译：人白介素10处理植入人胎胸腺和肝脏的SCID小鼠对急性体内人免疫缺陷病毒感染的抑制作用

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To improve the usefulness of in vivo models for the investigation of the pathophysiology of human immu- nodeficiency virus (HIV) infection, we modified the construc- tion of SCID mice implanted with human fetal thymus and liver (thy/liv-SCID-hu mice) so that the peripheral blood of the mice contained significant numbers of human monocytes and T cells.

机译：为了提高用于研究人类免疫缺陷病毒（HIV）感染的病理生理学的体内模型的有效性，我们修改了植入人类胎儿胸腺和肝脏的SCID小鼠（thy / liv-SCID-hu小鼠）的结构），以使小鼠的外周血中含有大量的人类单核细胞和T细胞。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3126-3131|共6页
作者
Tobias R. Kollmann; Massimo Pettoello-Mantovani; Nikos F. Katopodis;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. Gene therapy using a simian virus 40-derived vector inhibits the development of in vivo human immunodeficiency virus type 1 infection of severe combined immunodeficiency mice implanted with human fetal thymic and liver tissue. [J] . Goldstein H, ecom.yu.edu, Pettoello Mantovani M, The Journal of Infectious Diseases . 2002,第10期

机译：使用猿猴病毒40衍生的载体进行基因治疗可抑制植入人胎胸腺和肝组织的严重联合免疫缺陷小鼠体内人免疫缺陷病毒1型感染的发展。
2. Human Immunodeficiency Virus Type 1 Restriction by Human–Rhesus Chimeric Tripartite Motif 5α (TRIM 5α) in CD34+ Cell-Derived Macrophages In Vitro and in T Cells In Vivo in Severe Combined Immunodeficient (SCID-hu) Mice Transplanted with Human Fetal Tissue [J] . Joseph Anderson Ramesh Akkina Human Gene Therapy . 2008,第3期

机译：在人和胎儿组织严重混合的免疫缺陷（SCID-hu）小鼠体内，人-恒河猴嵌合三方体5α（TRIM5α）在CD34 +细胞衍生的巨噬细胞中和体内T细胞中对人类免疫缺陷病毒1型的限制。
3. Human immunodeficiency virus type 1 restriction by human-rhesus chimeric tripartite motif 5alpha (TRIM 5alpha) in CD34(+) cell-derived macrophages in vitro and in T cells in vivo in severe combined immunodeficient (SCID-hu) mice transplanted with human fetal tissue. [J] . Anderson J, Akkina R Human gene therapy . 2008,第3期

机译：在人类和人类胎儿组织移植的严重联合免疫缺陷（SCID-hu）小鼠体内，CD34（+）细胞衍生的巨噬细胞在体外和T细胞中，人类-恒河猴嵌合三方基序5alpha（TRIM 5alpha）对人类免疫缺陷病毒1型的限制。
4. Inhibition of human immunodeficiency virus type 1 infection in a T-cell line(CEM) by new dipeptidyl-peptidase IV (CD26) inhibitors [C] . J.D.Jiang, S.Willk, J.Li, Second workshop related to HIV/AIDS in China . 1999

机译：新的二肽基肽酶IV（CD26）抑制剂抑制T细胞系（CEM）中的人类1型免疫缺陷病毒感染
5. Modeling human immunodeficiency virus-1 (HIV-1) infection in the male reproductive tract (MRT) using humanized mice [D] . Fisher, Suhrim. 2016

机译：使用人源化小鼠模拟男性生殖道（MRT）中的人类免疫缺陷病毒1（HIV-1）感染
6. Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver. [O] . T R Kollmann, M Pettoello-Mantovani, N F Katopodis, 1996

机译：人白介素10处理植入人胎胸腺和肝脏的SCID小鼠对急性体内人免疫缺陷病毒感染的抑制作用。
7. Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver. [O] . Kollmann, T R, Pettoello-Mantovani, M, Katopodis, N F, 1996

机译：人白介素10处理植入人胎胸腺和肝脏的SCID小鼠对急性体内人免疫缺陷病毒感染的抑制作用。
8. CDC Guidelines for National Human Immunodeficiency Virus Case Surveillance,211 Including Monitoring for Human Immunodeficiency Virus Infection and Acquired 211 Immunodeficiency Syndrome. Morbidity and Mortality Weekly Report, Vol. 48, No. RR-211 13, Decem [R] . Fleming, P. L., Ward, J. W., Janssen, R. S., 1999

机译：疾病预防控制中心国家人体免疫缺陷病毒病例监测指南，211包括人类免疫缺陷病毒感染监测和获得性免疫缺陷综合症。发病率和死亡率周报，Vol。 48，编号RR-211 13，Decem

Inhibition of acute in vivo human immunodeficiency virus infection by human interleukin 10 treatment of SCID mice implanted with human fetal thymus and liver

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